他把钛合金植入自己手臂，“疯狂CEO”的人体实验

Core Viewpoint - Dane A. Miller, co-founder and long-time CEO of Biomet, demonstrated his commitment to the safety of titanium implants by personally having a titanium alloy implanted in his arm for ten years, which became a powerful testament to the trustworthiness of the materials used in orthopedic devices [3][10]. Group 1: Background and Education - Miller was born in Springfield, Ohio, and developed an early interest in engineering, eventually earning a bachelor's degree in mechanical engineering from Ohio State University and a master's and PhD in biomedical materials from the University of Cincinnati [6]. - His research focused on the biocompatibility of materials like titanium and tantalum, addressing the challenges of implant safety and integration with human bone [6]. Group 2: Founding Biomet - In 1977, Miller co-founded Biomet in Warsaw, Indiana, starting with a revenue of only $17,000 and operating from a converted barn [8]. - Unlike contemporaries that focused on mass production, Biomet emphasized custom implants tailored to surgeons' needs, quickly building a strong reputation in the industry [8]. - Under Miller's leadership from 1978 to 2006, Biomet grew to over $2 billion in annual revenue and employed more than 4,000 people, with flagship products like the AGC knee system setting industry standards [8]. Group 3: Trust through Personal Experience - To alleviate surgeons' concerns about the long-term safety of titanium implants, Miller had a titanium rod implanted in his arm, which he showcased at medical conferences, effectively using his experience as a marketing tool for Biomet [10]. - This personal experiment not only garnered attention but also established a narrative of trust and innovation around Biomet's products [10]. Group 4: Personal and Philanthropic Aspects - Miller's commitment to the field was personal, as his grandmother was the first patient to receive a total hip replacement from Biomet, highlighting the impact of his work on family and community [13]. - He and his wife established the Dr. Dane & Mary Louise Miller Foundation to support scholarships, community projects, and environmental initiatives [13]. Group 5: Legacy and Industry Impact - After stepping down in 2006 due to board conflicts, Miller regained control of Biomet in 2007 through a $11.4 billion acquisition with private equity partners [13]. - Biomet was acquired by Zimmer in 2015, forming Zimmer Biomet, and Miller passed away the same year, leaving behind a legacy as a pioneer in the orthopedic device industry [13]. - His approach combined trust and innovation, demonstrating the importance of risk-taking in advancing materials science and clinical practice [14].