美国一飞机坠毁！

Core Points - A plane crash occurred near Muhammad Ali International Airport in Louisville, Kentucky, on November 4, with significant smoke rising from the site [1] - UPS confirmed that one of its planes was involved in the accident, and both the FAA and NTSB will investigate the incident, with NTSB leading the inquiry [1] - Local police reported multiple injuries from the crash, and an emergency shelter-in-place order was issued for individuals within a five-mile radius of the airport [1]