切胃还能发胖？袖状胃切除术后体重反弹，警惕这一时间段高发

Core Insights - Obesity is a significant global public health issue, with a retrospective study revealing a 69.5% incidence of weight regain among patients who underwent sleeve gastrectomy (SG) [6][7] - The study identifies the third year post-surgery as a critical period for weight rebound, with 41.7% of patients experiencing a weight regain of 20% or more of their maximum weight loss, meeting the criteria for weight regain (WR) [6][7][8] Study Overview - The research included 676 patients who underwent SG at Shanghai Jiao Tong University from January 2011 to June 2022, with a median follow-up of three years [6][7] - Factors associated with higher postoperative total weight loss percentage (%TWL) included baseline age, initial BMI, male gender, and absence of hypertension [7] - Among 540 patients with complete follow-up at 1, 3, and 5 years, the rate of weight regain increased from 21.7% at year three to 32.6% at year five [7] Weight Change Patterns - Patients were categorized into three groups based on weight change trajectories: significant weight loss, moderate weight loss, and minimal weight loss [7] - The significant weight loss group had higher baseline BMI, waist circumference, fasting insulin, and insulin resistance index (HOMA-IR) compared to the minimal weight loss group [7] Implications for Future Research - The findings provide a scientific basis for identifying high-risk patients and developing preventive strategies against weight regain after SG [8]