最新研究发现：减重后科学食用“糖类”，有助于稳住体重且促进肠道健康

Core Insights - The article discusses the rising global obesity rates and the challenges of weight loss and maintenance, highlighting the role of sugar consumption and the controversial use of sweeteners in weight management [6][11]. Study Findings - A recent study published in Nature Metabolism provides new evidence on the effectiveness of sweeteners in weight management, showing that their reasonable use can help overweight or obese adults maintain weight loss while positively affecting gut health [7][11]. - The study involved 341 adults and 38 overweight or obese children over a one-year period, with participants initially undergoing a two-month low-energy diet before entering a ten-month weight maintenance phase [9]. - Participants were divided into two groups: one used sweetener-containing products to replace high-sugar foods, while the other maintained their usual sugar intake, both adhering to a diet where sugar contributed less than 10% of total energy [9]. Weight Maintenance Results - After one year, the sweetener group maintained an average weight loss advantage of 1.6 kg compared to the control group, with the weight difference consistently ranging from 1.0 to 2.1 kg throughout the study [9]. - Participants who strictly followed the intervention showed an even greater weight loss advantage of up to 3.7 kg [9]. Gut Health Benefits - The study also revealed that the sweetener group experienced significant increases in beneficial gut bacteria associated with short-chain fatty acids, along with enhanced microbial activity related to methane production and various fermentation processes [9][11]. - Metabolic pathway analysis indicated that the sweetener group exhibited more active beneficial metabolic activities, including the degradation of aromatic compounds and vitamin synthesis [9]. Safety Monitoring - The research team monitored the safety of sweetener use, noting that while the sweetener group reported more gastrointestinal discomfort, serious adverse events were rare and not directly linked to the intervention [11]. Conclusion - The findings support the use of sweeteners as a viable strategy for weight management and gut health improvement, offering hope for individuals struggling with weight regain [11].