体重大幅下降，糖友人生重启！《柳叶刀》重磅公布最新Meta分析：减重幅度与2型糖尿病缓解率呈正相关

Core Insights - A groundbreaking meta-analysis published in The Lancet Diabetes & Endocrinology reveals a strong dose-response relationship between weight loss and diabetes remission in overweight or obese patients with type 2 diabetes [6][9] Summary by Sections Weight Loss and Diabetes Remission - The study found that weight loss is crucial for controlling type 2 diabetes and reducing the risk of related complications, providing clear treatment goals and expected outcomes for clinicians and patients [9] - A systematic review of randomized controlled trials identified 22 high-quality studies, focusing on complete and partial remission metrics [7] Remission Rates Based on Weight Loss - Dramatic differences in complete remission rates were observed based on weight loss: only 0.7% of patients losing less than 10% of their body weight achieved complete remission, while nearly half (49.6%) of those losing 20%-29% and 79.1% of those losing over 30% achieved complete remission [7][8] - Partial remission rates also showed a clear ascending trend: 5.4% for less than 10% weight loss, 48.4% for 10%-19%, 69.3% for 20%-29%, and 89.5% for over 30% weight loss [7][8] Statistical Analysis - Each 1% reduction in body weight was associated with a 2.17% increase in the probability of complete remission and a 2.74% increase in the probability of partial remission [8] - The study did not find significant associations between remission outcomes and factors such as age, gender, race, disease duration, baseline body mass index, hemoglobin A1c levels, insulin use, or weight loss intervention methods [8]