Financial Data and Key Metrics Changes - The company has sufficient cash to complete its trials, with an expected cash runway extending into 2028, indicating no immediate financial overhang [8] Business Line Data and Key Metrics Changes - The lead compound, ABTX009, is currently in Phase 2b of the LOTUS trial, with results expected in mid-2026 [7] - The company is targeting hidradenitis suppurativa (HS), a severe skin disease, with a significant unmet medical need [5][12] Market Data and Key Metrics Changes - The HS market is evolving, with new therapies emerging, but there remains a substantial unmet need for more effective treatments [11][12] - The market for HS is projected to grow significantly, with conservative estimates suggesting it could reach $10 billion by 2035 [42] Company Strategy and Development Direction - The company aims to transition rapidly into Phase 3 trials following the Phase 2 results, with a potential BLA filing anticipated around 2029 [34] - The strategy includes differentiating ABTX009 from competitors by focusing on its higher potency and longer half-life compared to existing therapies [6][22] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the mechanism of action of ABTX009, highlighting its potential to treat additional immune-mediated inflammatory diseases [8] - The management noted that dermatologists are increasingly looking for new therapies due to the limitations of current treatments, indicating a favorable environment for new entrants [35][38] Other Important Information - The trial design for ABTX009 is similar to that of other recent studies, with a focus on clinically relevant endpoints [27] - The company is studying a diverse patient demographic across the US, Canada, Australia, and Europe, which may help in achieving robust treatment effects [31] Q&A Session Summary Question: Can you discuss the current state of HS and the effectiveness of emerging therapies? - Management highlighted that HS is a severe disease with significant pain and disability, and there is a growing recognition of the need for better therapies [11] Question: What differentiates ABTX009 from other IL-1 strategies? - Management emphasized that targeting IL-1 beta specifically is advantageous, as it plays a pivotal role in chronic inflammation associated with HS [20][21] Question: What are the expectations for the Phase 2 trial data readout in 2026? - The study is powered to show a placebo-subtracted efficacy rate of 25-30%, with a robust treatment effect expected [28][30] Question: How does the company plan to carve out a commercial niche in the HS market? - Management believes that with a differentiated side effect profile and superior efficacy, ABTX009 can capture a significant share of the market [39][42] Question: What are the potential additional indications for IL-1 beta? - Management mentioned several potential indications, including Crohn's disease and rheumatoid arthritis, highlighting the broad applicability of IL-1 beta targeting [43][44]

Core Insights - EUROAPI has signed a share purchase agreement for the sale of 100% of EUROAPI UK Ltd, which operates the Haverhill manufacturing site, to Particle Dynamics [1][2] - The divestment is part of EUROAPI's strategy to optimize its industrial footprint and advance its FOCUS-27 transformation plan, enhancing efficiency and focus on its strategic network [2] - The Haverhill site generated approximately 35 million euros in net sales in 2024, with nearly 80% attributed to Sanofi [2] Company Overview - EUROAPI is a leading player in active pharmaceutical ingredients, offering around 200 products and developing innovative molecules through its Contract Development and Manufacturing Organization (CDMO) activities [3] - The company operates six manufacturing sites in Europe and supplies customers in over 80 countries, emphasizing high-quality API manufacturing [4] - EUROAPI is listed on Euronext Paris under the ticker EAPI [4]

1. 我国双航母圆满完成远海实战化训练。 2. 国家外汇局新发放一批QDII额度合计30.8亿美元。 3. 外交部：有条件恢复日本部分地区水产品进口。 4. 进一步深化金融服务新型工业化的相关政策有望研究出台。 5. 商务部回应加拿大政府关闭海康威视在加业务：中方对此强烈不满、坚决反对。 6. 财政部：境外投资者以分配利润直接投资符合条件的，可按照投资额的10%抵免相应税额。 1. 花旗：黄金市场的供应缺口预计将在2025年第三季度达到峰值，随后由于投资需求下降而逐渐减弱。 2. 美联储博斯蒂克：我仍然预计今年会有一次降息。预计明年将有三次降息。 3. 据CBS记者：美国总统特朗普将于周一签署一项行政命令，涉及放宽对叙利亚的制裁措施。 4. 美国财长贝森特：在7月9日截止日期前的最后一周，将会出现一波贸易协议的密集签署。 5. 美国总统特朗普：由于油价低迷，预计（乌克兰）将可以与俄罗斯达成停火协议。 金十数据整理：6月30日欧盘美盘重要新闻汇总 7. 商务部：自2025年7月1日起，对原产于欧盟、英国、韩国和印度尼西亚的进口不锈钢钢坯和不锈钢热 轧板/卷继续征收反倾销税，实施期限为5年。 国际新闻： 国内新闻 ...

It’s the final day of the first half of 2025, and market indexes are once again at all-time highs on the S&P 500 and Nasdaq, closing-in on the Dow and small-cap Russell 2000. We’re also roughly +20% from near-term lows, in early April of this year. In short, it’s been quite a rollercoaster ride for investors. We are light on economic prints today, but not for the week: despite a shortened trading week in observance of Independence Day on the 4th of July Friday, this is Jobs Week: including a new Job Opening ...

当地时间6月30日20时50分左右，由上海飞往成田的日航8696航班波音738客机在关西机场紧急降落。据 日本国土交通省大阪航空局确认，机上191名乘客及机组人员均未受伤或出现身体不适。根据日本国土 交通省等部门通报，飞机触发显示"增压系统故障"的警报。机舱内疑似发生减压状况，飞行员向空管宣 布紧急状态，随后变更目的地降落关西机场。（央视新闻） ...

2024年6月30日，世界级跨海工程——深中通道正式通车，这条横跨珠江口，连接深圳、中山和广州的交通大动 脉，不仅改写了粤港澳大湾区的通勤格局，更成为推动产业协同、促进区域融合发展的"黄金走廊"。通车一年 来，深中通道总车流量超过3155万车次，日均超过8.64万车次，约占珠江口日过江总车流量的五分之一。 通勤革命：从"双城记"到"同城化" 陈先生在深圳前海上班，家人住在珠江西岸的江门，周末或有事时回家，以往的路线是先北上绕道东莞，过虎门 大桥后再南下江门。这样的行驶路线在深中通道通车后有了巨大改变，他可以从前海直接通过深中通道回家。"以 前回家需要差不多三个小时，堵车的时候更久，现在一个半小时就行了。"陈先生说。 在大湾区，和陈先生有着类似经历的不在少数，社交媒体上，很多跨城上班族分享了自己的通勤路线，并寻求一 起上下班的坐车"搭子"，以分担过路费，比如不少从南沙前往前海上班，全程不到50分钟。对他们来说，伴随着 珠江口的日升日落，头顶不时有飞机飞过，也是上下班路途中的一道亮丽的风景。 广东省交通运输厅、广东交通集团发布的数据显示，深中通道通车满一周年，总车流量超过3155万车次，日均超 过8.64万车次。 ...

财务数据显示，截至2025年03月31日，万国数据收入总额27.23亿人民币，同比增长11.96%；归母净利 润7.63亿人民币，同比增长320.64%。 大事提醒： 6月30日，万国数据(GDS)盘中上涨2.09%，截至23:40，报30.8美元/股，成交3087.73万美元，总市值 63.56亿美元。 本文源自：金融界 作者：行情君 8月20日，万国数据将披露2025财年中报（数据来源于纳斯达克官网，预计披露日期为美国当地时间， 实际披露日期以公司公告为准）。 资料显示，万国数据控股有限公司(纳斯达克股票代码:GDS;港交所股票代码:9698)是中国及东南亚地区 领先的高性能数据中心运营商和服务商。公司的数据中心分布于对高性能数据中心需求广泛的中国核心 经济枢纽地区。为了满足客户更广泛的需求,公司还根据客户的选择在非一线城市地区建设和运营数据 中心。公司的数据中心规模大,电力供应充沛、密度高且高效,所有关键系统均具备多重冗余。公司中立 于运营商及云服务提供商,客户可自由选择与主要电信运营商连接,以及接入托管于公司数据中心的多家 云服务提供商。万国数据可为客户提供托管和管理服务,包括与领先的公有云进行直接私 ...

智通财经6月30日电，GMS Inc大涨近12%创历史新高。消息面上，美国家居建材零售巨头家得宝近日 通过旗下专业贸易分销子公司SRS Distribution达成协议，将以每股110美元的价格收购GMS Inc全部流 通股。 ...

一项对32位交易员和分析师的调查显示，OPEC+预计将同意第四次增产41.1万桶/日，该增产将于8月生 效。此次增产是沙特阿拉伯试图夺回市场份额的努力之一。尽管燃料需求疲软且全球供应过剩迹象明 显，OPEC+仍在以最初计划的三倍速度恢复已暂停的产量。预计此举将给目前已接近每桶68美元的油 价带来下行压力，并加剧成员国的财政压力。（彭博） ...

自从某高考志愿填报服务网红横空出世以来，与高考志愿填报相关的服务渐成泛滥之势。不仅各种合法 机构打着"科技公司"的名号收取咨询服务费，而且掺杂了许多不明来历的网络博主也在从事收费服务。 志愿填报服务市场乱象丛生，有些考生和家长特别依赖网红效应和"AI智能"噱头的引导，花了钱却没有 得到满意的服务。 除了"货不对板"之外，更严重的问题在于：某些服务宣扬缺乏长远眼光的短期、功利选择。缺乏长远眼 光的价值宣扬最大的问题是使考生放弃人生价值的生命性思考，或者说丧失了对人生意义的思考。 当前，高校各专业历年录取情况都是公开的，就业率也是公开的。大学及社会机构里有专门从事就业问 题研究的学者，他们已发表的研究成果和调研报告也都是可以查询到的。至少这些材料都可以整合到平 台数据库中。数据库也可以开发出一些免费的或收费的综合信息服务，比如大学及各专业的排名、各专 业的师资与成就、某专业的就业趋势、大学生就业去向、行业就业预警之类的网络服务信息。 平台搭建和使用过程中，也不妨用上AI工具，使平台更方便地获取和整合资料，这些资料又可以方便 家长和考生运用AI提取。这种服务远比当前社会上杂乱无章的服务更靠谱、更专业、更贴合实际需 ...