UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 _____________________________________________ ____________________________________________ Title of each class Trading Symbol(s) Name of each exchange on which registered FORM 10-K _____________________________________________ ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT 1934 For the fiscal year ended December 31, 2021 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF ...

Financial Data and Key Metrics Changes - Twilio reported strong financial results for Q4 2021, with a year-over-year revenue growth of 54% to $842 million, and a full-year revenue of $2.84 billion, representing a 61% increase [9][16][70] - The company expects to achieve non-GAAP operating profitability in 2023, driven by improvements in operating expenses and gross margins over time [16][19][70] Business Line Data and Key Metrics Changes - The messaging business grew organically by 52% year-over-year, while application services, including Segment, are growing at a faster rate [35][70] - Twilio's customer engagement platform, including products like Flex and Segment, is gaining traction with significant adoption among Global 2000 companies [9][41] Market Data and Key Metrics Changes - Twilio's presence in Global 2000 customers doubled since the end of 2020, indicating strong market penetration and growth potential [65] - International messaging volumes surged in Q4, attributed to both market investments and specific customer growth [60] Company Strategy and Development Direction - The company aims to become a leading software player that connects businesses to their customers, focusing on personalized engagement through its customer engagement platform [9][19] - Twilio is pursuing an "in and up" strategy, leveraging existing customer relationships to upsell additional services and products [23][41] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's growth trajectory, citing broad-based strength across the business and a positive setup for 2022 and beyond [57] - The focus on first-party data and privacy regulations is seen as a significant trend that will drive customer engagement and retention [14][15] Other Important Information - The company is refining its guidance philosophy to provide more consistent and accurate forecasts based on improved insights into customer usage patterns [25][27] - Twilio is exploring potential M&A opportunities but remains focused on organic growth and enhancing its existing product offerings [62][64] Q&A Session Summary Question: Adoption of solution-based products - Management is pleased with the adoption of software solutions like Flex and Segment, noting significant customer success stories [12][13] Question: Path to profitability in 2023 - Profitability will come from a combination of operating expense management and improved gross margins as the company scales [16][19] Question: Go-to-market strategy for 2022 - The sales team is being trained to leverage the "in and up" strategy to expand existing customer relationships [23][24] Question: Insights on guidance philosophy - The company has gained better insights into customer usage, allowing for more accurate forecasting [25][27] Question: Drivers behind international growth - International market investments and specific customer volume increases contributed to the surge in international messaging [60] Question: Growth prospects for Segment - Segment is expected to drive significant growth, with strong customer traction and integration with other products [58] Question: Strategy for Engage product - Engage aims to provide a data-driven approach to marketing, addressing the limitations of legacy marketing automation tools [66][67]

Twilio Inc. (NYSE:TWLO) Q3 2021 Earnings Conference Call October 28, 2021 5:00 PM ET Company Participants Jeffrey Lawson - Co-Founder and CEO George Hu - COO Marc Boroditsky - CRO Khozema Shipchandler - CFO Andrew Zilli - Vice President of Investor Relations Conference Call Participants Meta Marshall - Morgan Stanley Frederick Havemeyer - Macquarie Rishi Jaluria - RBC Capital Markets Samad Samana - Jefferies Derrick Wood - Cowen Michael Turrin - Wells Fargo Securities Ittai Kidron - Oppenheimer & Co Parker ...

Financial Data and Key Metrics Changes - Twilio reported a strong growth rate of 50% to 52% for Q3 guidance, indicating robust performance expectations moving forward [15] - The company experienced broad-based strength across various facets of the business, particularly in messaging and application services [19][51] - The dollar-based net expansion rate showed significant improvement, reflecting strong revenue contributions from new customers [50] Business Line Data and Key Metrics Changes - The messaging product continued to deliver outstanding results, with reacceleration noted over previous periods [25][51] - Segment, a key acquisition, had a strong quarter, contributing positively to overall growth despite some sequential growth fluctuations [25][61] - Flex, the cloud contact center solution, is experiencing rapid adoption across a diverse range of customers, indicating its strong market position [75] Market Data and Key Metrics Changes - International revenue saw a notable uptick, attributed to ongoing global expansion efforts and the acquisition of ValueFirst, which contributed entirely to international revenue [17] - The company noted that only about 15% of the contact center market has transitioned to the cloud, highlighting significant growth opportunities ahead [76] Company Strategy and Development Direction - Twilio is focused on enhancing its product offerings through strategic acquisitions, such as Zipwhip, to improve service capabilities and expand market reach [34][36] - The company is committed to supporting digital transformation initiatives, emphasizing a land-and-expand strategy that allows customers to start with one use case and expand to others [32] - The integration of Segment Journeys aims to improve customer engagement by leveraging first-party data, aligning with current privacy trends [40][42] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the future, citing strong customer demand and the ongoing digital transformation as key drivers for growth [19][76] - The company acknowledged challenges in the IoT space due to global supply chain issues but remains confident in long-term growth prospects as 5G technology rolls out [56] - Management highlighted the importance of building trusted communications and enhancing customer relationships through innovative messaging solutions [35][68] Other Important Information - Twilio committed $10 million to Gavi, the Vaccine Alliance, to support global vaccination efforts, showcasing its corporate social responsibility initiatives [10] - The company is actively exploring M&A opportunities that align with its product roadmap and customer needs [29][30] Q&A Session Summary Question: Insights on Segment's co-selling and growth - Management noted that co-selling efforts are just beginning and will take time to reflect in financials, but they are optimistic about future growth [14][17] Question: Strongest outperformance areas in the quarter - Management highlighted broad-based strength, particularly in messaging and Segment, with strong net expansion and new customer growth [19] Question: International revenue growth drivers - The uptick in international revenue is attributed to global expansion and the acquisition of ValueFirst, which contributed fully in Q2 [17] Question: M&A strategy and balance between organic and inorganic growth - Management emphasized the importance of aligning acquisitions with customer needs and product roadmap to accelerate growth [29][30] Question: Flex adoption in contact centers - Flex is experiencing rapid growth, with adoption across various customer segments, indicating a strong market position [75] Question: Update on IoT business and Super SIM - Management expressed optimism about the IoT business, highlighting the potential of Super SIM to simplify global device connectivity [53][56]

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 _____________________________________________ FORM 10-Q _____________________________________________ ____________________________________________ ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT 1934 For the quarterly period ended June 30, 2021 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-37806 __ ...