Group 1 - The Hong Kong biopharmaceutical sector experienced a collective rise, with WuXi Biologics (02269.HK) and Junshi Biosciences (01877.HK) leading the gains, both increasing over 9% [1] - Other companies such as WuXi AppTec (02359.HK), Kanglong Chemical (300759.HK), Kelun Pharmaceutical (06821.HK), and Tigermed (03347.HK) also saw increases of 4%-5% [1] Group 2 - A significant ruling by the U.S. International Trade Court on May 28 declared the "day of liberation" tariff policy from the Trump administration unconstitutional, reducing policy uncertainty for Chinese pharmaceutical companies looking to expand overseas [3] - The ruling emphasized that the U.S. Constitution grants Congress exclusive power to regulate trade, limiting presidential authority in economic security matters [3] Group 3 - The first quarter of 2025 saw a surge in License-out transactions, totaling 41 deals worth approximately $36.93 billion, nearing the total for the entire year of 2023 [3] - Notable transactions included 3SBio's $12.5 billion upfront payment plus up to $4.8 billion in milestone payments to Pfizer for a PD-1/VEGF dual antibody drug [3] Group 4 - The upcoming ASCO annual meeting in Chicago is expected to showcase the international competitiveness of Chinese innovative drugs, with 71 studies from Chinese companies selected for oral presentations [4] - Key clinical data will be released by several prominent companies, including Innovent Biologics and China Biologic Products, which may reshape treatment standards for non-small cell lung cancer [4][5] Group 5 - The progress of ADC drugs developed by partners of WuXi Biologics and collaborations between Kelun Pharmaceutical and Merck is also attracting attention [5] - The increasing quantity and quality of results presented by Chinese pharmaceutical companies at top academic platforms like ASCO indicate a recognized research and development capability in oncology [5]

教育股也普遍上扬。其中，中教控股（00839.HK）涨8.7%，新东方-S（09901.HK）涨4.32%,思考乐教 育（01769.HK）涨2.56%,卓越教育集团（03978.HK）涨2.74%。 节假日概念股、体育用品、奢侈品股、香港零售股等消费股走高。美团-W（03690.HK）涨6.62%，消 息面，美团闪购618发布了酒品类首日战报，自5月28日启动以来的24小时内，酒类整体成交额相比增长 超18倍。同程旅行（00780.HK）涨4.34%，携程集团-S（09961.HK）涨3.51%，安踏体育（02020.HK） 涨4.18%，361度（01361.HK）涨3.49%。 稳定币概念板块午后爆发，其中，连连数字（02598.HK）飙升44.86%，众安在线（06060.HK）大涨 31.56%。消息面，美国副总统万斯5月28日表示，本届政府不认为稳定币会威胁美元的完整性。恰恰相 反，将其视为美国经济实力的倍增器。此外，近期香港立法会三读通过的《稳定币条例草案》。今年年 底前，合规的香港稳定币有望正式落地。 短视频概念、明星科网股等均表现活跃。快手-W（01024.HK）涨4.94%，京东集团-SW ...

Core Viewpoint - Waterdrop Inc., known for its crowdfunding platform "Waterdrop Fundraising," is facing growth challenges despite a slight revenue increase in 2024. The company's main business, insurance, shows limited growth potential, and its recent expansion into CRO (Contract Research Organization) services is also under pressure due to industry competition and regulatory challenges [2][6][23]. Group 1: Company Overview - Waterdrop Inc. is primarily an insurance company that uses its crowdfunding platform to drive traffic to its insurance services, which has been a key part of its business model [2][9]. - The company has experienced a decline in revenue from 30.71 billion RMB in 2021 to 23.41 billion RMB in 2023, with a slight recovery expected in 2024 [12]. - The insurance business has consistently accounted for over 85% of the company's total revenue from 2021 to 2024 [9]. Group 2: Financial Performance - The insurance-related revenue for Waterdrop Inc. was 30.71 billion RMB in 2021, 25.59 billion RMB in 2022, and 23.41 billion RMB in 2023, indicating a downward trend [12]. - Operating profit from the insurance segment has also declined from 10.35 billion RMB in 2021 to 4.77 billion RMB in 2024 [12]. - In 2024, the company reported a slight increase in overall revenue, but the growth was primarily driven by a reduction in losses from its crowdfunding business [14]. Group 3: CRO Business Development - Waterdrop Inc. expanded into the CRO business in 2022, which initially showed promise with a revenue increase of approximately 68% in 2023 [4][20]. - However, in 2024, the CRO business revenue declined by 9.4%, reflecting a challenging market environment and increased competition [4][21]. - The CRO segment's performance is under pressure due to tightening budgets from pharmaceutical companies and a competitive landscape dominated by established players [21][23]. Group 4: Challenges and Risks - The company's crowdfunding platform, Waterdrop Fundraising, has faced scrutiny due to issues with trust and transparency, impacting its ability to convert traffic into insurance sales [10][11]. - Recent controversies, including fraudulent fundraising cases, have led to a crisis of credibility for both the platform and the parent company [11]. - The increase in service fees for the crowdfunding platform may negatively affect donor trust and subsequently the conversion rates to insurance products [14][15].

Group 1: Market Performance - Major indices experienced a strong rebound, with the Shanghai Composite Index rising by 0.7%, Shenzhen Component Index by 1.24%, and ChiNext Index by 1.37% [2] - Over 4,200 stocks in the two markets saw gains, with a total trading volume of approximately 1.19 trillion yuan [2] Group 2: Digital Currency and Software Sector - The digital currency and software sectors led the market rally, with notable stocks like Lakala (300773.SZ) and Sifang Jingchuang (300468.SZ) hitting the daily limit with a 20% surge [2] - New Guodu (300130.SZ) rose over 14%, while Feitian Chengxin (300386.SZ) and Shenzhou Information (000555.SZ) also saw significant increases of 12.84% and 10%, respectively [2] Group 3: Autonomous Driving and Intelligent Connected Vehicles - Stocks related to autonomous driving and intelligent connected vehicles surged, with companies like Fulongma (603686.SH) and Jintour Environment (001230.SZ) hitting the daily limit [3] - A strategic cooperation agreement was signed between Xiaoma Zhixing and Guangzhou Public Transport Group, focusing on autonomous vehicle services [3] Group 4: Innovative Pharmaceuticals - The innovative pharmaceutical sector remains active, with companies like Sanofi Guojian (688336.SH) rising over 12% [4][3] - The sector is supported by policy backing, global competitiveness, and improving fundamentals, with a focus on "innovation + internationalization" [4] Group 5: Automotive Sector - The automotive sector showed strong performance, with Jinlong Automobile (600686.SH) and Dongfeng Co. (600006.SH) both increasing by 10% [5] - The launch of new models by XPeng and supportive government policies in Fujian province are contributing factors to the sector's growth [5] Group 6: Weak Sectors - The precious metals and food processing sectors experienced declines, with companies like Western Gold (601069.SH) and Laiyifen (603777.SH) seeing significant drops [5]

Core Insights - The CXO sector has shown significant improvement in Q1 2025, marking a recovery from the previous year's downturn [1] - WuXi AppTec (药明康德) reported a remarkable revenue increase of 21.0% year-on-year to 9.65 billion yuan, with net profit soaring by 89.1% to 3.67 billion yuan [1] - The order volume for CXO companies has rebounded, with WuXi AppTec's total orders reaching 52.33 billion yuan, up 47.1% year-on-year [1] Company Performance - WuXi AppTec's Q1 revenue and net profit growth highlights its strong market position and operational efficiency [1] - Kanglong Chemical (康龙化成) also performed well, with a revenue increase of 16.03% to 3.099 billion yuan and a net profit growth of 32.54% to 306 million yuan [1] - In contrast, Tigermed (泰格医药) faced a decline in revenue by 10.58% to 6.603 billion yuan and a significant drop in net profit by 42.13% to 855 million yuan in 2024 [2][3] Challenges Faced by Tigermed - Tigermed's clinical trial services segment saw a revenue decline of 23.75% to 3.178 billion yuan, primarily due to funding issues faced by clients [2] - The company experienced a drastic drop in gross margin, with Q4 gross margin plummeting to 17.7% [2] - Non-operating losses turned negative at -476 million yuan in 2024, reflecting the impact of a downturn in the biopharmaceutical investment environment [2] Regional Performance - Tigermed's domestic revenue fell by 17.11%, significantly outpacing the 3.29% decline in international markets [3] - Despite a slight revenue recovery in Q1 2025, the overall growth trend remains weak due to increased competition [3][5] Strategic Adjustments - Tigermed is attempting to streamline operations by cutting unprofitable business lines and focusing on core services, but these adjustments are seen as insufficient [3][4] - The company is exploring AI integration to enhance efficiency, but current efforts have not yet yielded significant improvements in profitability [3][7] Industry Trends - Leading CXO firms like WuXi AppTec and Kelaiying (凯莱英) are establishing competitive advantages through high-end service offerings and technological integration [6][8] - WuXi AppTec's TIDES business saw a staggering revenue increase of 187.6% to 2.24 billion yuan in Q1 2025 [6] - The overall pricing environment in the CXO industry has been under pressure, with service prices dropping to about 70% of 2022 levels [8] Market Outlook - The industry is experiencing a structural shift, with top firms leveraging high-value services and global expansion to maintain competitiveness [8] - Current market valuations have adjusted to a PE range of 10-20 times, reflecting a recalibration of profit growth expectations [8]

Core Viewpoint - The Hong Kong pharmaceutical outsourcing sector is experiencing a strong performance, with notable increases in stock prices for several key companies [1] Company Performance - WuXi Biologics (02269.HK) has seen a stock price increase of 4.70% [1] - Kelun Pharmaceutical (06821.HK) has risen by 4.62% [1] - Tigermed (03347.HK) has gained 1.89% [1] - WuXi AppTec (02359.HK) has increased by 1.36% [1]

简历显示：葛兰女士:中国籍。美国西北大学生物医学工程专业博士。历任国金证券股份有限公司研究 所研究员,民生加银基金管理有限公司研究员。2014年10月加入中欧基金管理有限公司,曾任研究员、中 欧明睿新起点灵活配置混合型证券投资基金基金经理(2015年1月29日起至2016年4月22日)、中欧瑾泉灵 活配置混合型证券投资基金基金经理(2015年3月16日起至2016年4月22日)、中欧瑾源灵活配置混合型证 券投资基金基金经理(2015年3月31日起至2016年4月22日)、中欧瑾和灵活配置混合型证券投资基金基金 经理(2015年4月13日起至2016年4月22日)。现任中欧医疗健康混合型证券投资基金基金经理(自2016年9 月29日起至今),中欧明睿新起点混合型证券投资基金基金经理(自2018年7月12日起至今)、中欧阿尔法混 合型证券投资基金基金经理(2020年8月20日起至2023年9月28日)。 来源：金融界 金融界2025年5月28日消息，中欧医疗创新股票C(006229) 最新净值1.2024元，下跌1.30%。该基金近1个 月收益率4.79%，同类排名69|801；近6个月收益率17.61%，同类排 ...

此外，百货业股、啤酒、婴童用品、体育用品、节假日概念、航空股、奢侈品股等消费股均有不同程度 的上涨。其中，百威亚太（01876.HK）涨4.14%，青岛啤酒股份（00168.HK）涨1.81%，澳优 （01717.HK）涨2.56%，中国飞鹤（06186.HK）涨2.3%，中国东方航空股份（00670.HK）涨3.4%，中 国南方航空股份（01055.HK）涨2.56%。 SaaS概念股普遍承压。金山软件（03888.HK）跌6.49%，汇通达网络（09878.HK）跌3.67%，中国软件 国际（00354.HK）跌2.55%。 涨幅榜上，阿里影业（01060.HK）涨11.54%，欢喜传媒（01003.HK）涨7.5%，IMAX中国 （01970.HK）跟涨。随着端午节、六一儿童节和暑假三个节假期的集中到来，电影市场逐渐活跃起 来。截至目前，端午档预售票房破千万，好莱坞电影《碟中谍8：最终清算》领跑。电影业内人士认 为，倘若端午档的表现令人惊喜，将助力市场热度向暑期档平稳过渡，也能为行业和市场注入更多信 心。 短视频概念股、明星科网股等表现活跃。快手-W（01024.HK）绩后涨5.95%，网易-S（099 ...

Group 1 - The core viewpoint of the news is the performance and holdings of the China Europe Medical Innovation Stock A fund, which has shown significant growth in recent months and year-to-date [1] - As of May 27, 2025, the latest net value of the fund is 1.2806 yuan, reflecting a growth of 2.16% [1] - The fund's one-month return is 4.86%, ranking 291 out of 1022 in its category, while the six-month return is 17.27%, ranking 46 out of 987 [1] - Year-to-date, the fund has achieved a return of 23.16%, ranking 32 out of 999 [1] Group 2 - The top ten holdings of the China Europe Medical Innovation Stock A fund account for a total of 75.62%, with major positions including WuXi AppTec (10.35%), Kelun-Biotech (10.15%), and WuXi Biologics (9.82%) [1] - The fund was established on February 28, 2019, and as of March 31, 2025, it has a total scale of 4.675 billion yuan [1] - The fund manager is Ms. Ge Lan, who has extensive experience in the investment management field [2]

Group 1 - The core viewpoint of the news is the performance and holdings of the China Europe Medical Health Mixed Fund C, which has shown a recent net value increase and varying returns over different time frames [1] - As of May 27, 2025, the fund's latest net value is 1.5582 yuan, reflecting a growth of 0.85% [1] - The fund's one-month return is 3.03%, ranking 1106 out of 4652 in its category, while its six-month return is 0.23%, ranking 3299 out of 4496 [1] - Year-to-date, the fund has achieved a return of 2.43%, ranking 2140 out of 4544 [1] Group 2 - The top ten stock holdings of the fund account for a total of 55.30%, with significant positions in companies such as Heng Rui Pharmaceutical (10.60%), WuXi AppTec (9.95%), and Kanglong Chemical (6.24%) [1] - The fund was established on September 29, 2016, and as of March 31, 2025, it has a total scale of 15.566 billion yuan [1] - The fund manager, Ge Lan, has a background in biomedical engineering and has held various positions in research and fund management since joining China Europe Fund Management in 2014 [2]