Group 1 - The core idea of the research is the development of a "protein cage" that can encapsulate cytotoxic drugs used in chemotherapy, enhancing their targeted delivery and reducing side effects [1][2] - The research is led by Dr. Taylor Szyszka and Associate Professor Yu Heng Lau from the University of Sydney, and the findings have been published in the journal "Angewandte Chemie International Edition" [1] - The protein cage, specifically a subclass known as "shelled protein," was initially discovered in bacteria in compost in 2019 and is characterized by its stability and ability to protect its contents [1][2] Group 2 - The researchers successfully encapsulated the chemotherapy drug doxorubicin within the enhanced shelled protein, marking the first successful assembly of this type [2] - The previous method of loading drugs into shelled proteins was inefficient and compromised stability, as it required disassembly and reassembly [2] - Future research will focus on modifying the protein structure to enable the shelled protein to recognize and enter specific cells, such as liver cells for liver disease treatments [4]