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傅里叶叠层显微技术(FPM)
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曦光仪器首款傅里叶全景多模态数字显微镜正式发布,开启科研范式新时代
仪器信息网· 2025-07-14 03:33
Core Viewpoint - The article highlights the launch of the first Fourier panoramic multimodal digital microscope by Xiguang Instrument, which boasts 100% independent intellectual property rights and offers advantages such as high resolution, large field of view, super depth of field, and rapid imaging, enabling multimodal imaging from micro to mesoscopic levels [1][2]. Group 1: Technology and Innovation - The new generation of computational optical imaging technology, Fourier Layered Microscopy (FPM), significantly reduces hardware complexity and costs while achieving high-performance imaging through innovative LED array lighting and advanced algorithms [3][5]. - The Fourier panoramic multimodal digital microscope incorporates the principle of "animal compound eyes" into its optical design, featuring a programmable LED light source array that captures light information from multiple angles, achieving a maximum resolution close to 200nm, with customizable options reaching 150nm [6][7]. - The imaging system supports various imaging modes, including bright field imaging, quantitative phase imaging, and polarization imaging, and can be integrated with laser confocal and Raman spectroscopy for comprehensive applications in life sciences and clinical diagnostics [7][10]. Group 2: Applications and Market Potential - The FPM technology has shown significant advancements in applications such as cell biology, tissue pathology, and cancer early screening, providing high-resolution imaging that enhances diagnostic accuracy and efficiency [9][10]. - The technology's high-throughput imaging capability allows for rapid imaging and analysis of large cell populations, making it suitable for large-scale drug screening [9][10]. - Xiguang Instrument aims to expand its product framework, offering a range of instruments from portable detection devices to high-end drug screening instruments, and plans to introduce more innovative products for various fields, including semiconductors and materials science [10][13]. Group 3: Company Background - Xiguang Instrument is a leading provider of computational optical imaging technology solutions, collaborating with institutions like the Chinese Academy of Sciences to develop high-throughput and high-content digital microscopes for various applications in life sciences, medical diagnostics, and industrial testing [13].