Core Insights - The article highlights a significant breakthrough in single-cell mass spectrometry technology, marking a key advancement in China's high-end life science instruments [1][2]. Group 1: Technological Advancements - China has successfully developed a high-throughput, high-sensitivity single-cell mass spectrometer capable of automated qualitative and quantitative analysis of multi-polar metabolites within single cells [1]. - The new technology addresses limitations of traditional mass spectrometry devices, such as detection throughput, sensitivity, and compound coverage, which have previously hindered advancements in the field [1]. Group 2: Applications and Impact - The technology has significantly improved detection efficiency and data reliability, and is currently being demonstrated in basic life science research and clinical medicine [2]. - This advancement provides a solid technical foundation for enhancing China's capabilities in single-cell analysis and the development of high-end scientific instruments that are independently controllable [2].