Core Viewpoint - Long-term migraines may be associated with cardiac structural abnormalities, particularly patent foramen ovale (PFO), which is a common heart condition that can lead to various neurological symptoms [1][2]. Group 1: Health Statistics and Conditions - As of 2023, over 330 million individuals in China suffer from cardiovascular diseases, with a rising prevalence [1]. - The incidence of migraines in patients with PFO is approximately five times higher than in the general population [1]. - PFO is present in about 20% to 34% of adults, often without noticeable symptoms [1]. Group 2: Medical Recommendations and Treatments - Patients experiencing unexplained headaches or dizziness, especially those with a history of stroke, are advised to undergo screening for PFO [2]. - If intervention is necessary, a minimally invasive procedure using a closure device is typically employed to close the PFO [2]. - Multidisciplinary collaboration in treatment is emphasized to enhance the management of complex conditions related to both cardiac and neurological health [2].