Core Insights - The research published in the journal "Cell" presents a groundbreaking study on the dynamic interactions between inhibitory neurons, vascular networks, and microglia in the embryonic mouse brain using a novel in vivo imaging technique [1][2] Group 1: Research Findings - The study developed a high-stability, multi-angle, long-term in utero imaging technique (IMEE) that allows for comprehensive observation of various indicators such as blood flow and cellular activity in the embryonic brain [1] - Researchers identified the migration patterns of excitatory and inhibitory neurons in the embryonic mouse cortex, revealing that newly formed excitatory neurons migrate radially through multipolar migration, displacement movement, and cell body transport [1] - The findings provide new in vivo evidence for neuronal migration abnormalities in models of neurodevelopmental diseases and elucidate the dynamic behavior of embryonic immune cells in response to environmental stress [1] Group 2: Methodological and Application Value - The established technical system and analytical methods are expected to become important tools for future research on brain development and developmental brain diseases, indicating significant methodological value and broad application prospects [2] - The application of this technology in autism model mice has directly observed abnormal neuronal migration and demonstrated that embryonic microglia can rapidly sense damage and initiate repair [2]