Core Insights - The article discusses a pioneering clinical study at the Army Medical University’s Xinqiao Hospital, focusing on the use of Vagus Nerve Stimulation (VNS) to treat upper limb motor dysfunction in chronic ischemic stroke patients [1][2] - The study aims to provide new treatment pathways for stroke patients suffering from upper limb functional impairments, which are a significant cause of disability in China [1] Group 1: Treatment Mechanism - VNS involves implanting a miniature stimulator in the neck of stroke patients to activate the vagus nerve, enhancing brain plasticity and rebuilding damaged motor pathways [1] - The mechanism of VNS treatment includes activating the brainstem nucleus and promoting the release of neurotransmitters like acetylcholine and norepinephrine, which are crucial for motor function recovery [1] Group 2: Clinical Study Results - Eleven stroke patients have been enrolled in the study, with seven completing the main treatment phase [2] - The average improvement in upper limb motor function scores was 11.7 points, representing a 37.9% enhancement compared to pre-treatment levels [2] - Other significant improvements included a 121.7% increase in stroke impact scale scores, a 26.2% enhancement in daily living activity scores, and a 10.6-point increase in overall recovery ratings [2]