心脏移植技术突破

Search documents
新技术为心脏移植供体短缺解困
Huan Qiu Wang Zi Xun· 2025-07-22 07:16
Core Insights - Recent studies published in the New England Journal of Medicine highlight significant breakthroughs in low-cost cardiac resuscitation and preservation techniques developed by American surgical teams, addressing the organ donor shortage issue for transplants [1][2] Group 1: Cardiac Resuscitation Technology - Duke University team has developed an extracorporeal cardiac resuscitation system that pumps oxygenated blood into the aorta, successfully reviving a deceased infant's heart for transplantation into another infant, with normal heart function observed post-surgery [1] - The system was first validated in pig models before achieving its first human transplant this year, marking a significant advancement in pediatric heart transplantation [1] Group 2: Cardiac Preservation Technology - Vanderbilt University team has created a cardiac preservation technique that involves injecting a cooling oxygenated solution into the heart, allowing it to enter a "relaxed hibernation" state before transplantation, with positive outcomes observed in adult recipients [2] - Initial results show stable heart function without rejection in the first three adult recipients after six months, with subsequent surgeries yielding similarly positive results, indicating applicability for both adults and children [2] Group 3: Ethical and Technical Implications - These innovations overcome ethical and technical limitations associated with traditional organ procurement methods, providing critical support for expanding the donor pool in the field of organ transplantation [2]