Core Insights - A new microscopy technology developed by the University of California, Santa Cruz, has achieved breakthroughs in rapid 3D imaging, enabling real-time observation of cellular dynamics within small biological organisms [1][2] - The M25 system utilizes 25 synchronized cameras to capture images from different focal planes simultaneously, overcoming the limitations of traditional microscopy methods [1][2] Group 1: Technology Overview - The M25 system can capture data in a 3D space of up to 180×180×50 micrometers at a frame rate exceeding 100 volumes per second, achieving real-time imaging capabilities [1] - A custom diffraction optical element is the core of the system, which splits incoming light and directs it to the 25 cameras, each corresponding to an independent focal plane [1] Group 2: Applications and Benefits - The M25 system is particularly suitable for observing embryonic development and the movement of small model organisms, providing a new tool for analyzing biological neural systems [2] - It allows for full tracking of organisms like Caenorhabditis elegans and Drosophila melanogaster in 3D space, which was previously limited to partial observations [2] - The system can be easily integrated into standard commercial microscopes without the need for additional specialized hardware, lowering the technical barriers for adoption [2]