Core Viewpoint - The World Health Organization's Africa office reports the spread of monkeypox across multiple African countries, with the emergence of mutated strains, particularly the IIb variant found in Gambia and Mozambique [1] Summary by Sections Monkeypox Variants - The IIb variant of monkeypox has been identified in patients from Gambia and Mozambique [1] - Other variants such as Ia and Ib have been reported in Central Africa, while the Ib variant has been noted in East Africa [1] Current Situation - Over the past six weeks, 21 African countries have experienced ongoing monkeypox outbreaks [1] - Despite effective control measures in Sierra Leone and the Democratic Republic of the Congo, Uganda is witnessing an increase in cases [1] Global Context - A total of 79 countries worldwide have reported monkeypox cases, with 30,022 confirmed cases and 119 deaths attributed to the disease [1]