Core Viewpoint - The article discusses the rising popularity of probiotics marketed as anti-allergy solutions amid the seasonal allergy peak, questioning their efficacy and whether they can replace conventional allergy medications [1] Group 1: Mechanism of Allergies - Seasonal allergies are complex immune disorders influenced by genetics, environment, and individual immune status, leading to the release of inflammatory mediators like histamine upon re-exposure to allergens [2] - Common allergy medications like cetirizine and loratadine work by blocking histamine receptors to prevent allergy symptoms [2] Group 2: Probiotics and Allergy Relief - Certain specific strains of probiotics may theoretically help modulate the immune system and improve gut barrier function, potentially offering some anti-allergy effects [3] - However, the mechanisms by which probiotics may alleviate allergies are not fully understood, and there is a lack of sufficient evidence from clinical studies [3] Group 3: Efficacy of Probiotic Products - Many probiotic products claim to contain various strains, but the effectiveness depends on the specific strains and their scientific backing rather than the number of strains [4] - Some studies suggest that specific strains like Lactobacillus rhamnosus GG and Bifidobacterium longum BB536 may assist in preventing food allergies and eczema, but these findings are still exploratory and lack consensus [4] Group 4: Regulatory Concerns - Many "anti-allergy" probiotics are sold through cross-border e-commerce and may not comply with domestic safety assessments, raising concerns about their safety [5] - Current regulations in China do not recognize "anti-allergy" as a permissible health claim for food products, meaning that companies must provide substantial evidence to support such claims [5] Group 5: Health Risks of Misuse - Some allergy sufferers may be tempted to replace conventional medications with probiotics, which poses health risks as there is no evidence that probiotics can substitute for allergy medications [6] - Probiotics should only be considered as adjuncts to standard treatments, particularly during allergy flare-ups when immediate medication is necessary [6] Group 6: Consumer Guidance - Consumers should verify the product's attributes, ensuring it has the appropriate regulatory approvals and that the claimed benefits align with approved health functions [6][7] - It is essential to focus on the scientific research supporting specific strains rather than being misled by marketing claims about the number of strains or their origin [7]