Core Viewpoint - The article presents a new method for simultaneously determining trichloroacetic acid (TCAA) and perchlorate in water samples using an SH-AP-2 anion exchange column and ion chromatography with suppressed conductivity detection, achieving reliable results within 23 minutes [2][3][28]. Methodology - The method utilizes an SH-AP-2 anion exchange column with a mobile phase of 5% methanol and 15.0 mmol/L Na2CO3 at a flow rate of 0.80 mL/min, allowing for effective separation of common anions in water [3][10][28]. - The linear relationship between peak area or height and concentration for both TCAA and perchlorate is established within the range of 0.05 to 5.0 mg/L, with correlation coefficients between 0.9996 and 0.9999 [4][16]. Results - The method demonstrates good recovery rates for TCAA and perchlorate, ranging from 98.2% to 101.3% and 98.3% to 102.7%, respectively, with relative standard deviations (RSD) below 6% [4][21][23]. - The detection limits for TCAA and perchlorate are 0.04 mg/L and 0.02 mg/L, respectively, indicating high sensitivity of the method [4][16]. Instrumentation and Conditions - The ion chromatography system includes a CIC-100 ion chromatograph and a self-regenerating suppressor, with specific settings for temperature and current to optimize performance [5][6]. - The choice of mobile phase and flow rate significantly impacts the retention time and separation efficiency of the analytes, with optimal conditions established through systematic testing [10][12][13]. Conclusion - The developed method is efficient, reproducible, and suitable for environmental monitoring of TCAA and perchlorate in water samples, providing a quick and reliable analytical tool for assessing water quality [28].