Market Overview - The Nasdaq 100 index has seen a decline of 1%, while the Dow Jones Industrial Average has dropped by 800 points, marking a decrease of 1.88% [1] - The yield on the 10-year U.S. Treasury bond has increased by 10 basis points, reaching a high of over 4.6%, the highest level since February 13 [1] Company Performance - Palo Alto Networks Inc (PANW) shares decreased by $11.98, closing at $182.5 [2] - MicroStrategy (MSTR) shares fell by $18.04, with a closing price of $398.88 [2] - Shopify Inc (SHOP) shares dropped by $3.65, ending at $102.78 [2] - Palantir Technologies Inc (PLTR) saw a decline of $4.16, closing at $121.43 [2] - Vertex Pharmaceuticals Inc (VRTX) shares decreased by $13.28, closing at $433.9 [2] - IDEXX Laboratories Inc (IDXX) shares fell by $14.12, closing at $503.04 [2]