Core Insights - An international research team has developed a new type of brain implant called the microfluidic axial electrode, which can precisely deliver drugs to different regions of the brain, potentially advancing research on epilepsy and complex brain functions like memory and decision-making [1][2] Group 1: Device Design and Functionality - The microfluidic axial electrode is designed to distribute functions along its axis, allowing for simultaneous optical stimulation, electrical signal recording, and drug delivery at multiple depths, unlike traditional devices that operate at a single endpoint [1] - Made from soft polymer optical fibers, the new electrode closely resembles brain tissue, reducing mechanical damage and chronic rejection, which are common issues with traditional silicon-based implants [1][2] - The electrode's tip features a special angled design that minimizes damage to brain tissue during insertion, achieving higher precision and lower trauma [1] Group 2: Manufacturing and Testing - The manufacturing process of the microfluidic axial electrode involves a technique similar to "pulling sugar," where a large polymer rod is heated and stretched into ultra-fine fibers with a diameter of less than half a millimeter [2] - The internal structure of the electrode includes a central light-conducting core surrounded by eight microfluidic channels, enabling precise injection of different drugs or chemicals into brain regions within 3 millimeters of each other [2] - Successful experiments on mice demonstrated that the implanted electrodes allowed for free movement without noticeable discomfort, enabling simultaneous monitoring of electrical activity in both the cortex and hippocampus [2] Group 3: Future Implications - With further optimization, the microfluidic axial electrode is expected to become a crucial tool for studying brain disease mechanisms and developing closed-loop neuroregulation therapies [3]