Allegations and Charges - Dr James Craig is accused of poisoning his wife Angela's protein shakes in 2023 [1] - Craig pleaded not guilty to first-degree murder and other charges [1] Evidence and Investigation - Toxicology report found acute cyanide, ingredients from over-the-counter eye drops, and arsenic in Angela's autopsy [2] - An affidavit alleges Craig purchased arsenic on Amazon [2] - Craig's online searches included "how many grams of pure arsenic will kill a human" and "is arsenic detectable in autopsy" [3] - Court documents allege Craig searched YouTube for "top five undetectable poisons that show no signs of foul play" and "how to make poison" [3] Defense Arguments - The defense acknowledged financial woes and claimed Angela contributed to them [2] - The defense revealed Craig's extramarital relationships but argued it doesn't prove murder [2]