TABLE OF CONTENTS As filed with the Securities and Exchange Commission on January 12, 2026 Registration No. 333-292581 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Hyung Heon Kim President, Chief Executive Officer and Director 545 Concord Avenue, Suite 210 Cambridge, Massachusetts 02138 (857) 702-9600 (Name, address, including zip code, and telephone number, including area code, of agent for servic ...

Table of Contents FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 TEMPEST THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Delaware 2834 45-1472564 (Primary Standard Industrial Code Number) As filed with the Securities and Exchange Commission on December 9, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 (I.R.S. Employer Identification Number) 2000 Sierr ...

Classification Code Number) As filed with the Securities and Exchange Commission on September 25, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 NLS PHARMACEUTICS LTD. (Exact name of registrant as specified in its charter) | Switzerland | 3841 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | incorporation or organizatio ...

As filed with the Securities and Exchange Commission on August 27, 2024 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 NLS Pharmaceutics Ltd. (Exact name of registrant as specified in its charter) | Switzerland | 3841 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | | incorporation or organization) | Classification Code Numb ...