Core Viewpoint - WuXi Biologics has entered into a license and research service agreement with Vertex Pharmaceuticals for the development of a trispecific T-cell Engager aimed at treating B-cell mediated autoimmune diseases [1][2]. Group 1: Agreement Details - Vertex Pharmaceuticals will have exclusive global rights to develop and commercialize the trispecific T-cell Engager at the preclinical stage [2]. - WuXi Biologics will receive an upfront payment and is eligible for additional milestone payments related to development, regulatory approvals, and sales, along with royalty payments [2]. Group 2: Company Overview - WuXi Biologics is a leading global Contract Research, Development, and Manufacturing Organization (CRDMO) that provides end-to-end solutions for biologics from concept to commercialization [4]. - The company employs over 12,000 skilled professionals across multiple countries, including China, the United States, Ireland, Germany, and Singapore, and is currently supporting 945 integrated client projects, with 74 in Phase III and 25 in commercial manufacturing as of December 31, 2025 [5]. Group 3: Commitment to Sustainability - WuXi Biologics emphasizes sustainability as a key component of long-term business growth, focusing on green technology innovations to provide advanced Green CRDMO solutions [6]. - The company is dedicated to achieving excellence in Environment, Social, and Governance (ESG) practices and collaborates with stakeholders to promote positive social and environmental impacts [6].

The project aims to strengthen Ethiopia’s status as Africa’s air-travel hub and help return the country to a path of stability and development after years of internal strife. But there are doubts about its viability https://t.co/XnIhnCsYMsPhoto: AFP https://t.co/kmmJ0x8YGw ...

RT Jacob Creech (@jacobvcreech)Solana development continues to evolveOver the next 6 months, I expect devs will:- use Wincode + zerocopy, not borsh- use sbpf-linker, not forks- send to the leader TPU, not RPC- include privacy by default in their appsSolana devs are leveling up ...

Heritage & Development - The central question is whether to prioritize heritage preservation or accept its loss as the cost of progress, suggesting a need to find a balance [5] - The presentation advocates for a third path: developing differently by integrating memory, protecting what must be protected, and adapting what can be adapted [14] - The talk emphasizes that heritage in Bandar Seri Begawan is a living, moving part of life, not just a static museum exhibit [6] - The presentation highlights the resilience of Kampong Ayer, showcasing how it continues to thrive as a living story of a society [8] Community & Partnership - The presentation suggests mentorship programs where elders teach younger generations traditional skills like fishing, house building on water, and boat construction [10] - The presentation proposes floating classrooms to teach biodiversity and water quality, while also repurposing waste [11] - The presentation emphasizes the importance of partnerships across sectors and generations (SDG17) to preserve heritage [12] - The presentation stresses that preserving heritage requires collaboration between archivists, architects, youth, the elderly, government, civil service, civic society, and small business owners [12] Future & Identity - The presentation commemorates the 55th anniversary of the renaming of Bandar Brunei to Bandar Seri Begawan, emphasizing the importance of honoring the past while moving forward [15] - The presentation concludes by questioning the purpose of progress if it means losing cultural roots [16]

🚨 THETA NETWORK'S LATEST PROGRESS - Despite market downturns, @Theta_Network hasn't slowed its development... Catch up on its most important recent updates https://t.co/f7o3FtHWlx ...

Overcoming Adversity and Achieving Dreams - The speaker recounts a personal journey of recovery from severe post-traumatic stress disorder following a road traffic accident [1] - The journey involved overcoming fear, anxiety, and depression to fulfill a dream of driving from the United Kingdom to India [3][9] - The speaker drove solo through 32 countries in 57 days, covering 35,383 kilometers [4] Expedition Details and Challenges - The expedition included driving through nine mountain ranges, nine time zones, the Arctic Circle, and three major deserts [5] - The speaker acted as their own mechanic and doctor, performing car repairs and administering first aid in remote locations [6] - Pre-expedition preparations included cooking and freezing two months' worth of meals for the family [7] Inspiring Others and Personal Growth - The journey was described as a pilgrimage and a conversation with oneself, emphasizing personal exploration and growth [8][9] - The speaker highlights the importance of overcoming fear and taking journeys within oneself to inspire and motivate others [10] - The speaker emphasizes that anything is possible with determination and that individuals have the power to overcome their own challenges [9][10] Positive Interactions and Humanity - The speaker shares instances of kindness and help received from strangers along the way, highlighting the positive aspects of humanity [16][19] - Examples include a family in Kyistan offering a meal and a mechanic in China fixing a car suspension for free [16] - The speaker also mentions being treated favorably at the Russia-Latvia border due to being perceived as Indian [17][18][19]

In the coming year Africa will enter a new phase of aid and development. But it may have to wait for a new generation of leaders for it to truly begin https://t.co/Bpsrdxjg69 ...

Key Takeaways on Risk-Taking and Social Entrepreneurship - Social entrepreneurship involves taking risks [1] - Taking risks can define one's journey [3] - It's crucial to find time to figure out what one wants to do in life [4] Footsteps Organization Impact - Footsteps has helped almost 1 million people graduate from extreme poverty [2] - The Thrishna water project ensures safe water for over 400,000 people daily across Bangladesh through 300+ systems [8] - A World Bank project to set up drinking water facilities for waste workers led to cleaning up a 2-kilometer canal in 72 hours [9][11] Qualities for Successful Risk-Taking - Courage and determination are essential for success when taking risks [12] - Stubbornness to stick by the risk is crucial; giving up leads to failure [13] - Not accepting failure and embracing trial and error can lead to success [13]

Every Indian state promises development, but most exercise authority from the top down. Few give ground-level officials any autonomy. Kerala is an exception https://t.co/wkRWSw6iGh ...

Kerala’s status as a development superstar is commendable. But its model would be even more impressive if it could also power growth https://t.co/wxbgPVchhnIllustration: Lan Truong https://t.co/qleDCdxRCg ...