Drug discovery targeting human aging

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BioAge Labs Expands Drug Discovery Platform with Data from Leading European Biobank
GlobeNewswire News Roomยท 2025-06-17 13:00
Core Insights - BioAge Labs, Inc. is launching an initiative to analyze over 17,000 samples from the HUNT Biobank in Norway to enhance drug target discovery for aging-related diseases [1][2][3] Company Overview - BioAge is a clinical-stage biotechnology company focused on developing therapeutic candidates for metabolic diseases by targeting human aging biology [5] - The lead product candidate, BGE-102, is an orally available small-molecule NLRP3 inhibitor aimed at obesity, showing significant weight loss in preclinical models [5] Research Initiative - The collaboration with Age Labs AS will profile samples from over 6,000 HUNT participants, generating millions of molecular readouts to expand BioAge's proprietary aging data [2][3] - The analysis will focus on participants with long-term health records, tracking the transition from health to diseases such as cardiometabolic disease (>50% of participants) and cognitive decline (>35%) [3] Data Utilization - Insights from the HUNT profiling will integrate into BioAge's existing discovery platform, which has over 50 million molecular measurements collected over five decades [4] - This initiative aims to accelerate the identification of therapeutic targets that promote physiological resilience against age-related diseases [4]