Tariff Impact Analysis - President Trump's new 100% tariffs on the pharma sector may not be as severe as initially feared due to bilateral trade agreements and manufacturing presence in the United States [1][2] - The tariff impact is mitigated because many pharmaceutical manufacturers have operations or are building facilities in the United States [2] - Tariffs on materials used in drug manufacturing in the United States are a small portion of the overall cost, with gross margins on these products being 85-90% plus [4] - The API (Active Pharmaceutical Ingredient) component may only be 1-2% of the overall cost, so a 10-15% tariff on that component is not a major concern [5] Investment Recommendations - The industry is more focused on the IRA (Inflation Reduction Act) negotiated price list and potential drug pricing negotiations [5] - Gilead is viewed favorably due to its long-acting prep launch [6] - Fizer's recent deal is seen as a positive step, but execution is needed [7] - Other favored names include Vert [6]

Core Viewpoint - President Trump's new tariffs on the pharmaceutical sector may not have a significant negative impact due to existing manufacturing in the U.S. and bilateral trade agreements that could mitigate the effects [1][2][3]. Tariff Implications - A 100% tariff is proposed, but it does not apply to pharmaceutical manufacturers with U.S. operations, which includes nearly all companies in the sector [2]. - The potential tariff's impact on the cost of goods sold, particularly on active pharmaceutical ingredients (API), is minimal since APIs constitute only about 1-2% of the overall cost of pharmaceutical products [4][5]. Market Reactions - The stock market does not seem overly concerned about the tariffs, indicating a level of confidence among investors [1]. - The focus is shifting towards the upcoming IRA negotiated price list and potential drug pricing negotiations that could affect pricing strategies [5]. Company Insights - Gilead is highlighted as a strong investment opportunity due to the positive outlook on their long-acting prep launch [6]. - Pfizer is also noted for a recent deal that may signal a recovery from previous challenges, although execution remains a key factor for success [6].