Table of Contents As filed with the Securities and Exchange Commission on March 27, 2024 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 (Primary Standard Industrial Nevada 2834 45-0692882 Classification Code Number) (I.R.S. Employer Identification Number) 11250 El Camino Real, Suite 100 San Diego, CA 92130 FORM S-1 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 SKYE BIOSCIENCE, INC. (Exact Name of Registrant as Specified in its Charter) (State or other ...