GCMS分析方法开发

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GCMS Solution工作站的COAST功能使用简介
仪器信息网· 2025-10-02 03:58
Core Viewpoint - The article emphasizes the efficiency improvements in GCMS method development through the use of the COAST (Create Automatic SIM Table) function, which automates the creation of SIM tables, thereby reducing manual workload and enhancing analysis speed [3][4][16]. Summary by Sections Overview of COAST Function - The COAST function in Shimadzu's GCMS Solution workstation significantly enhances the efficiency of analysis method development by automating the creation of SIM tables [4][16]. - Traditional method development involves multiple manual steps, which can be cumbersome, especially with complex samples [3]. Basic Operation Steps for COAST - The basic steps to create a SIM method using COAST include: 1. Creating a Scan method file by setting the GCMS to Scan mode and analyzing a high-concentration standard sample [6][7]. 2. Processing the data file to identify chromatographic peaks and creating a component table [8]. 3. Returning to the real-time analysis module to open the saved method file and selecting the option to automatically create the MS table [11][12]. 4. Saving the analysis method file for data collection [14] [16]. Advanced Features of COAST - The COAST function allows for the simultaneous collection of scan and SIM data, known as FASST, and can also create sub-ion scanning methods and MRM methods when using triple quadrupole GCMS [16][17]. - This flexibility in data collection modes enhances the analytical capabilities of the GCMS system [16].