Gene therapy for heart failure
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Medera to Present Late-Breaking Phase 1/2a Clinical Trial Results at Heart Failure 2025 Congress
GlobeNewswire News Roomยท 2025-05-12 12:00
Company Overview - Medera Inc. is a clinical-stage biopharmaceutical company focused on developing next-generation therapeutics targeting cardiovascular diseases [7] - The company operates through two business units: Novoheart and Sardocor, which are involved in preclinical and clinical development respectively [7][10] Clinical Trial Information - Medera's MUSIC-HFpEF clinical trial is investigating the gene therapy candidate SRD-002 for heart failure with preserved ejection fraction (HFpEF) [1][2] - The trial utilizes a proprietary minimally invasive intracoronary infusion methodology for the one-time gene therapy treatment [2] - The trial data will be presented at the Heart Failure 2025 Congress in Belgrade, Serbia, on May 18, 2025 [1][3] Heart Failure Context - Heart failure is a global pandemic with approximately 64.3 million cases worldwide, with HFpEF accounting for nearly half of these cases [2][6] - There is a significant unmet medical need for disease-modifying therapeutics for HFpEF, as current treatments have limited success [6] Industry Significance - The Heart Failure Congress is a leading event that covers the entire spectrum of heart failure, providing a platform for advancements in treatment and research [4] - The presentation of the MUSIC-HFpEF trial at this congress highlights the importance of addressing the critical needs in heart failure treatment [4] Future Developments - Medera has entered into a definitive merger agreement with Keen Vision Acquisition Corporation (KVAC), which is focused on biotechnology opportunities [5][12] - The merger aims to enhance Medera's capabilities in developing therapeutics for difficult-to-treat diseases [5][12]