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Merck Advances Oncology Innovation, Highlighting Progress in New Tumor Types and Earlier Stages of Disease at ESMO 2025
Businesswire· 2025-10-09 10:45
Presentations at the Congress will feature new or updated findings from Merck's broad portfolio of cancer medicines, including data for KEYTRUDA (pembrolizumab); LENVIMA (lenvatinib), in collaboration with Eisai; WELIREG (belzutifan); and KEYTRUDA QLEXâ"¢ (pembrolizumab and berahyaluronidase alfa- pmph). Key data being presented on existing medicines in Merck's portfolio: Additionally, new data for investigational antibody-drug conjugates (ADCs) from Merck's innovative pipeline will be presented at the Cong ...
Remarkable Gains in the Stock Market: A Closer Look at Top Performers
Financial Modeling Prep· 2025-10-08 22:00
Core Insights - Several companies have experienced significant stock price increases, attracting investor attention and market analysis [1] Company Summaries - **Xenetic Biosciences, Inc.**: Achieved a 142.31% increase in stock price, closing at $10.39, with a trading volume of 45,373,947. The company focuses on immuno-oncology technologies and has expanded its partnership with The Scripps Research Institute to advance CAR T-cell therapies [2] - **bioAffinity Technologies, Inc.**: Stock price rose by 108.60% to $0.48, with a volume of 29,850. The company specializes in non-invasive cancer diagnosis and treatment, showcasing the clinical value of its CyPath® Lung in detecting early-stage lung cancer [3] - **GigCapital7 Corp.**: Recorded an 89.43% increase in stock price, ending at $1.58. This SPAC is gaining interest due to its business combination with BigBear.ai, which has a pro forma enterprise value of $1.378 billion and aims to capitalize on AI/ML market opportunities [4] - **AlphaTON Capital Corp.**: Experienced an 85.48% rise in stock price to $10.35. The company is transitioning to a digital asset treasury model focused on Toncoin (TON) and is exploring the tokenization of single-indication economics for mesothelioma [5] - **Acurx Pharmaceuticals, Inc.**: Stock price increased by 74.36% to $7.48. The company is developing antibiotics for bacterial infections and received a positive opinion from the European Medicines Agency for its Pediatric Investigation Plan, positioning it for international Phase 3 clinical trials [6] Market Dynamics - The performances of these companies illustrate the dynamic nature of the stock market and the potential for significant returns, prompting investors and analysts to monitor future developments closely [7][8]
GT Biopharma Provides Enrollment Update on GTB-3650 Phase 1 Trial in Patients with Relapsed or Refractory (r/r) CD33 Expressing Hematologic Malignancies
Globenewswire· 2025-10-08 13:00
The Company is well on track with Phase 1 enrollment now that both patients in Cohort 3 have successfully initiated treatment with no evidence of dose-limiting toxicities or tolerability concerns to date The first patient in Cohort 3 has shown promising evidence of immune activation consistent with levels of activity observed in patients from the previous two lower-dose cohorts; additional update anticipated by year-end Upon successful completion of the Cohort 3 safety assessment, the trial will continue to ...
Aptevo Presenting Scientific and Clinical Updates at SITC and ASH, also Participating in Leading Financial and Industry Conferences in the Fourth Quarter
Accessnewswire· 2025-10-08 12:20
SEATTLE, WASHINGTON / ACCESS Newswire / October 8, 2025 / Aptevo Therapeutics ("Aptevo" or the "Company") (Nasdaq:APVO), a clinical-stage biotechnology company developing novel bispecific and trispecific immuno-oncology therapeutics, today announced its participation in upcoming key financial, industry, scientific and medical conferences this fall, providing the opportunity to highlight continued momentum and recent developments among a broad range of stakeholder audiences. These conferences include: 4th An ...
Anixa Biosciences Announces Completion of Final Patient Visit in Breast Cancer Vaccine Clinical Trial
Prnewswire· 2025-10-07 12:30
Final Clinical Visit Marks Major Milestone in First-in-Human Evaluation of Breast Cancer Vaccine Comprehensive Immune Response and Safety Data to Be Presented at the San Antonio Breast Cancer Symposium in December , /PRNewswire/ -- Anixa Biosciences, Inc. ("Anixa" or the "Company") (NASDAQ: ANIX), a biotechnology company focused on the treatment and prevention of cancer, today announced the completion of the final patient visit in its breast cancer vaccine clinical trial. This novel vaccine, invented at Cle ...
GT Biopharma to Participate in the Centurion One Capital 3rd Annual Bahamas Summit
Globenewswire· 2025-10-06 13:00
SAN FRANCISCO, CALIFORNIA, Oct. 06, 2025 (GLOBE NEWSWIRE) -- GT Biopharma, Inc. (the “Company”) (NASDAQ: GTBP), a clinical stage immuno-oncology company focused on developing innovative therapeutics based on the Company's proprietary natural killer (NK) cell engager TriKE® platform, today announced that Michael Breen, Executive Chairman and Chief Executive Officer of GT Biopharma, will be participating in the Centurion One Capital 3rd Annual Bahamas Summit at the Rosewood Baha Mar Hotel from Tuesday, Octobe ...
ALX Oncology to Present Updated Data from Phase 2 ASPEN-06 Trial, Highlighting CD47 Expression as a Predictive Biomarker in HER2+ Gastric Cancer, at 40th Society for Immunotherapy of Cancer (SITC) Annual Meeting
Globenewswire· 2025-10-03 13:05
Company will share data demonstrating CD47 overexpression as key predictive biomarker for response with the Company’s lead candidate, evorpacept, in HER2+ gastric cancer SOUTH SAN FRANCISCO, Calif., Oct. 03, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapies designed to treat cancer and extend patients’ lives, today announced updated data from its Phase 2 ASPEN-06 (NCT05002127) ...
Coherus Oncology Announces Poster Presentation at the 40th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
Globenewswire· 2025-10-03 13:05
– CHS-114, an anti-CCR8 cytolytic antibody, will also be featured in SITC’s upcoming webinar series “Targets for Cancer IO: A Deep Dive” on October 22, 2025 –REDWOOD CITY, Calif., Oct. 03, 2025 (GLOBE NEWSWIRE) -- Coherus Oncology, Inc. (NASDAQ: CHRS), today announced an upcoming poster presentation at the 40th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) being held November 5-9, 2025, in National Harbor, Maryland. Abstract # 640: CHS-114, an anti-CCR8 cytolytic monoclonal antibody demon ...
OPKO Health, Inc. (OPK)’s ModeX Division Pushes Four Immuno-Oncology Candidates into Phase 1
Yahoo Finance· 2025-10-01 17:44
Core Insights - OPKO Health, Inc. is a diversified healthcare company involved in diagnostics, pharmaceuticals, and innovative therapies, with a focus on immuno-oncology and metabolic disorders [1] - The company has seen significant insider buying in 2025, indicating strong confidence from key shareholders in its long-term prospects [2] Company Developments - CEO Phillip Frost, the largest shareholder with approximately 31% ownership, has participated in recent share purchases, increasing the top five holders' combined ownership to 51% [2] - OPKO is advancing a Phase 1 Epstein-Barr virus vaccine in collaboration with Merck, with potential Phase 2 trials starting next year [3] - The ModeX division is innovating in immuno-oncology with four candidates in the pipeline, including MDX2001, currently in Phase 1 trials [3] Product Pipeline - OPKO is addressing obesity through a collaboration with Entera Bio on OPK-88006, an oral dual GLP-1/glucagon agonist, with promising results presented at ENDO 2025 [4] - The company is developing both oral and injectable formulations to meet the increasing demand for obesity treatments [4] Financial Performance - OPKO reported Q2 2025 revenue of $156.8 million, a decline from the previous year, but is projected to achieve revenues of $640–$660 million for 2025 [5] - The recent sale of select oncology testing assets to Labcorp aims to streamline operations and improve liquidity [5] - The company is focusing on its pipeline, cost savings, and strategic divestitures to enhance margins and move towards profitability [5]
Full renewal of the Board of Directors Election of Dr. Markus Cappel as Chairman of the Board of Directors
Globenewswire· 2025-09-30 17:30
Core Points - OSE Immunotherapeutics held its Annual General Meeting, where shareholders representing approximately 56% of the share capital and over 62% of voting rights participated in key decisions for the company's future [1] - Dr. Markus Cappel was elected as the new Chairman of the Board of Directors, expressing enthusiasm for advancing the company's promising pipeline and novel medicines [3] - The company has a strong pipeline of innovative drug candidates and has achieved positive clinical trial results, positioning it as a significant player in the immunotherapy landscape [4] Board of Directors - The shareholders voted in favor of appointing new directors, including Dr. Markus Cappel and Alexis Peyroles [2] - The new Board of Directors held its first meeting post-election and confirmed its confidence in the employees' commitment to developing novel medicines [5] Dr. Markus Cappel's Background - Dr. Markus Cappel has over thirty years of experience in the biotechnology sector and is recognized for his entrepreneurial spirit and achievements [6] - As Chief Business Officer of ChemoCentryx, he led product development and negotiations that secured commercial rights and development control in the U.S. [7] - He played a key role in ChemoCentryx's acquisition by Amgen for $4 billion, which represented a 116% premium [8] Company Overview - OSE Immunotherapeutics is dedicated to developing first-in-class assets in immuno-oncology and immuno-inflammation, addressing unmet patient needs [11] - The company collaborates with leading academic institutions and biopharmaceutical companies to bring transformative medicines to market [11]