Thailand is making a last-ditch effort to avert a punitive 36% export levy with offers of greater market access for US farm and industrial goods https://t.co/eKwocWnWaM ...

[Music] Most trades in modern financial markets are not decided by strategy or by logic or any other metric. The largest metric which are decided upon is time. Latency is described as the delay between sending information from one place to another.Now, as Max Versstappen, who's a racer for the Formula 1 Red Bull team, described, the only place that matters is first. And similarly, or more humorously, Ricky Bobby said, "The if you ain't first, you're last." Now, this modern financial markets are very depende ...

Teva Pharmaceutical Industries (TEVA) 2025 Conference June 04, 2025 09:20 AM ET Speaker0 Good morning. Welcome to the Jefferies Healthcare Conference in New York, day one. My name is Dennis Thing, biotech analyst, here at Jefferies. I have the great pleasure of having Teva here with us. Welcome. So maybe to I think there's a little bit of feedback, but maybe just help level set us in terms of where the business is right now and how the business has evolved over the last several years and some of the investm ...

OREM, Utah, May 15, 2025 (GLOBE NEWSWIRE) -- Reflect Scientific, Inc. (Symbol: RSCF), a provider of innovative cryogenic technologies for the life sciences and biotech industries, today announced that it is actively transitioning from the OTCQB Venture Market to the OTCIQ platform. This move is designed to streamline regulatory compliance and strengthen communication with investors. The transition to OTCIQ reinforces Reflect Scientific's ongoing commitment to transparency, growth, and long- term shareholder ...

Harrow (HROW) Q1 2025 Earnings Call May 09, 2025 08:00 AM ET Company Participants Jamie Webb - Director of Communications & Investor RelationsMark Baum - Chief Executive Officer and Chairman of the BoardAndrew Boll - Chief Financial OfficerJeffrey Cohen - MD - Equity ResearchYi Chen - Managing Director, Equity ResearchMayank Mamtani - Senior Managing Director Conference Call Participants Thomas Flaten - Senior Research AnalystChase Knickerbocker - Senior Equity Research Analyst - Healthcare Operator Good mo ...

Financial Data and Key Metrics Changes - The company reported total revenues of $197.1 million for Q1 2025, representing a year-over-year increase of 43% on an as-reported basis and 32% on an organic basis [8][28] - Adjusted non-GAAP EBITDA was $50.7 million, compared to $37.6 million in the prior year period, reflecting strong operational performance [32] - Adjusted non-GAAP EPS for the quarter was $1.7, up from $1.21 in the prior year period [32] Business Line Data and Key Metrics Changes - Revenues from the rare disease segment were $69 million, up 87% from the prior year, driven by strong performance of Cortrophin Gel, which generated $52.9 million in revenues, a 43% increase [29][30] - The generics segment reported revenues of $98.7 million, an increase of 41% year-over-year, attributed to new product launches and strong execution in the base business [14][30] - Revenues from the brands portfolio were $25.1 million, a slight decrease of 2% from the prior year [29] Market Data and Key Metrics Changes - The overall ACTH category grew 27% to approximately $684 million in 2024, indicating a favorable market environment for Cortrophin Gel [9] - The company expects Cortrophin Gel revenues to increase by 34% to 38% in 2025, projecting revenues of $265 million to $274 million [10][33] - The retina products, ILUVIEN and YUTIQ, generated revenues of $16.1 million in Q1, with performance impacted by market access challenges for Medicare patients [11][29] Company Strategy and Development Direction - The company is focused on expanding its rare disease business, particularly through Cortrophin Gel, and is investing in evidence generation and new product presentations to enhance market penetration [19][20] - A bespoke commercial approach is being implemented to address market access challenges, particularly for ILUVIEN and YUTIQ, with plans to enhance sales force capabilities [24][25] - The company is committed to maintaining a strong U.S. manufacturing footprint, with over 90% of revenues coming from domestically produced goods, positioning itself favorably in light of potential pharmaceutical tariffs [16][94] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the growth trajectory of Cortrophin Gel, citing a significant unmet medical need and a large addressable patient population [19][64] - The company anticipates a return to sequential revenue growth in the latter half of 2025, following a strong first quarter performance [34] - Management acknowledged challenges in the retina segment but highlighted positive trends in demand and a strengthened sales team as factors that will support future growth [13][53] Other Important Information - The company is preparing for an upcoming trial with CG Oncology regarding a royalty obligation dispute, with the jury trial set to commence on July 21, 2025 [36][38] - The company has a strong balance sheet with $149.8 million in unrestricted cash and a gross leverage ratio of 3.5 times [32] Q&A Session Summary Question: How much should the prefilled syringe help Cortrophin? - Management noted that early responses to the prefilled syringe have been positive, as it reduces one step in the administration process, and they expect to see traction as the year progresses [42][43] Question: What gives confidence in accelerating ILUVIEN and YUTIQ sales? - Confidence is based on several factors, including performance outside the U.S., improvements in sales force strength, and positive impacts from a bespoke commercial approach [51][52] Question: What are the payer dynamics for Cortrophin as the category returns to growth? - Management indicated that payers appreciate the competition brought to the category and that collaboration will continue to ensure patient access [82] Question: How is the acquisition of Alimera performing? - Management expressed confidence in the long-term opportunity for ILUVIEN and YUTIQ, highlighted by the recent buyout of a royalty obligation [84]

Financial Data and Key Metrics Changes - The company reported a 38% year-over-year revenue growth in Q1 2025, achieving $280 million in revenue guidance for the year [7][20] - Cash flow from operations reached a record $19.7 million in the first quarter [7] - The company aims to generate approximately $232 million in revenue over the remaining three quarters of 2025 [7] Business Line Data and Key Metrics Changes - Vevi revenue increased by 35% sequentially from $16 million in Q4 2024 to $21.5 million in Q1 2025, prior to the launch of the VIVI Access for All program [8][21] - iHizo's sales were impacted by destocking in Q1 2025, but unit sales more than doubled in April compared to the first quarter average, indicating a return to growth [16][22] - Triassence completed critical market access initiatives in Q1, leading to a doubling of accounts ordering the product since the beginning of the year [19] Market Data and Key Metrics Changes - The company noted seasonality in its business, with Q1 typically being the weakest revenue period [9] - The specially branded products faced challenges in gross to net estimates, affecting recognizable revenue [10] Company Strategy and Development Direction - The company is focused on achieving and potentially exceeding its 2025 revenue guidance through various product lines, including Vevi, iHizo, and Triassence [20][24] - The VIVI Access for All program is seen as a transformative initiative that could significantly impact revenue growth [12][14] - The company is not planning to exit the compounding business, emphasizing its importance in building commercial relationships and credibility [33][56] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in meeting revenue guidance, citing strong momentum in new prescriptions and refill rates for Vevi [21][24] - The company acknowledged challenges in the first quarter but expects significant improvement in subsequent quarters [58][92] - Management is optimistic about the long-term potential of its products and the overall business model [92] Other Important Information - The company is actively engaged in discussions for debt refinancing, aiming for a positive outcome by late summer or early fall [86][87] - The impact of current tariff policies on gross margins is estimated to be negligible, around 50 basis points [67][69] Q&A Session Summary Question: Price increase initiatives for iEZO - Management indicated that there were no significant price increases for iEZO, and some prices were actually decreased to enhance accessibility [26][29] Question: Project Beagle initiatives - Project Beagle aims to transition CLARITY C patients to Vevi, which is expected to be financially beneficial [30][31] Question: Sequential changes in iHizo - Management confirmed that unit demand for iHizo is returning to growth mode after destocking in Q1 [36][40] Question: Triassence volume inflection - Management noted that new accounts are opening and using Triassence, with positive signs for future growth [42][44] Question: Impact of tariffs on products - Management stated that the impact of tariffs on gross margins is minimal, around 50 basis points [67][69] Question: Transition of compounding products to prescription - Management highlighted the hidden value in the compounding business and its role in building commercial relationships [53][55] Question: Revenue dynamics for iHizo - Management acknowledged the need for improvement in revenue and unit demand for iHizo, with expectations for growth in 2025 [75][76] Question: VIVI patient transition from CLARITY - Management confirmed that over 25,000 patients are being transitioned from CLARITY C to Vevi, with positive feedback from KOLs [77][80] Question: Debt refinancing outlook - Management expressed confidence in achieving favorable terms for debt refinancing by late summer or early fall [86][87]

Financial Data and Key Metrics Changes - The company reported a 38% year-over-year revenue growth in the first quarter of 2025, achieving $280 million in directional revenue guidance for the year [6][20] - Cash flow from operations reached a record $19.7 million [6] - The company aims to generate approximately $232 million in revenue over the remaining three quarters of the year [6] Business Line Data and Key Metrics Changes - Vevi revenue increased by 35% sequentially from $16 million in Q4 2024 to $21.5 million in Q1 2025, prior to the launch of the VIVI Access for All program [7][12] - iHizo's sales were impacted by destocking in Q1 2025, but unit sales more than doubled in April compared to the monthly average in Q1 [15][16] - Triassence completed critical market access initiatives in Q1, leading to a doubling of accounts ordering the product since the beginning of the year [18][19] Market Data and Key Metrics Changes - The company noted seasonality in its business, with Q1 typically being the weakest revenue period [9] - The specially branded products faced challenges due to volatility in gross to net estimates, affecting recognizable revenue [10] Company Strategy and Development Direction - The company is focused on achieving and potentially exceeding its 2025 revenue guidance through various product lines, including Vevi, iHizo, and Triassence [6][20] - The VeeVai Access for All program is expected to significantly impact revenue growth, with the potential to become a leading product in the dry eye medication market [12][14] - The company is not planning to exit the compounding business, emphasizing its importance in building commercial relationships and credibility [32][34] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in meeting revenue guidance, citing strong momentum in new prescriptions and refill rates for Vevi [11][21] - The company anticipates that the third quarter will see stronger numbers driven by compounding effects from new prescriptions [23] - Management acknowledged the need for improvement in certain product lines and plans to review current strategies [59] Other Important Information - The company expects to deliver over $50 million in revenue from iHizo in 2025, with significant growth anticipated [22] - The ImprimisRx compounding business is projected to deliver more than $80 million in revenue in 2025 [22] Q&A Session Summary Question: Price increase initiatives for iHizo - Management indicated that there were no significant price increases for iHizo, and some price decreases were implemented to enhance accessibility [26][29] Question: Project Beagle initiatives - Management clarified that Project Beagle focuses on transitioning Clarity C patients to Vevi, which is expected to be financially beneficial [30][32] Question: Sequential changes in iHizo - Management noted that unit demand is returning to growth mode, with expectations for incremental growth in Q2 [38][41] Question: Triassence volume inflection - Management reported that many new accounts are beginning to use Triassence, with positive signs of adoption in various care settings [44][46] Question: Impact of tariffs on products - Management estimated a negligible impact of current tariff policies on gross margins, around 50 basis points [68][70] Question: Debt refinancing plans - Management expressed confidence in successfully restructuring debt by late summer or early fall, with positive discussions ongoing with lenders [85][86]