Key Takeaways Genmab shares jumped 21.9% in a month on plans to acquire Merus for $8 billion in cash.The acquisition adds petosemtamab, a late-stage oncology candidate, to GMAB's proprietary pipeline.GMAB expects petosemtamab to drive growth, with potential billion-dollar sales contributions by 2029.Shares of Genmab A/S (GMAB) have rallied 21.9% in a month. The stock price rally was observed after the company signed a definitive agreement in late September to acquire Merus N.V. (MRUS) for $97 per share in c ...

Core Insights - Jazz Pharmaceuticals has successfully acquired Chimerix, Inc. for approximately $935 million in cash, enhancing its oncology pipeline and commitment to addressing rare diseases with significant unmet needs [1][2][3] Acquisition Details - The acquisition was completed through a tender offer for Chimerix's outstanding shares at $8.55 per share, which expired on April 17, 2025 [3] - Following the acquisition, Chimerix became a wholly owned subsidiary of Jazz Pharmaceuticals [3] Product Development - The acquisition includes dordaviprone, a novel first-in-class small molecule treatment for H3 K27M-mutant diffuse glioma, which is currently under Priority Review by the FDA with a PDUFA action date set for August 18, 2025 [2][4] - If approved, dordaviprone may be the first FDA-approved therapy for this specific type of glioma and could offer a promising near-term commercial opportunity [2][4] Clinical Trials - Dordaviprone is being evaluated in the ongoing Phase 3 ACTION trial for newly diagnosed, non-recurrent H3 K27M-mutant diffuse glioma patients following radiation treatment, potentially expanding its use into first-line settings [2][4] Company Overview - Jazz Pharmaceuticals is a global biopharmaceutical company focused on developing life-changing medicines for serious diseases, with a diverse portfolio that includes therapies for sleep disorders, epilepsy, and cancer treatments [5]