Core Insights - Valneva SE and Serum Institute of India have mutually agreed to discontinue their license agreement for Valneva's single-shot chikungunya vaccine, allowing Valneva to regain full rights and control over its supply chain and commercialization efforts in endemic high-risk countries [1][2] Group 1: Company Overview - Valneva SE is a specialty vaccine company focused on developing, manufacturing, and commercializing prophylactic vaccines for infectious diseases, addressing unmet medical needs [5] - The company has advanced multiple vaccines from early R&D to approvals and currently markets three proprietary travel vaccines [6] - Valneva's revenue from its growing commercial business supports the advancement of its vaccine pipeline, which includes a Lyme disease vaccine candidate partnered with Pfizer and a Shigella vaccine candidate [7] Group 2: Chikungunya Vaccine Context - Chikungunya virus (CHIKV) is a mosquito-borne disease causing severe joint pain, fever, and other symptoms, with significant economic and medical burdens expected to grow due to climate change [3][4] - Since 2004, chikungunya has spread to over 110 countries, with more than 3.7 million cases reported in the Americas between 2013 and 2023, highlighting the disease as a major public health problem according to the WHO [4] Group 3: Strategic Partnerships and Funding - Valneva's strategic intent to regain rights to the chikungunya vaccine aligns with its commitment to support access in low-and-middle-income countries, as outlined in a funding agreement with the Coalition for Epidemic Preparedness Innovations (CEPI) [2] - CEPI aims to accelerate vaccine development and ensure equitable access, having supported over 70 vaccine candidates against high-risk pathogens [8] Group 4: Serum Institute of India Overview - Serum Institute of India is a global leader in vaccine manufacturing, with an annual capacity of 4 billion doses and a presence in over 170 countries [10][11] - The company focuses on producing affordable vaccines and has played a significant role in reducing the prices of essential vaccines, including those for Diphtheria, Tetanus, and COVID-19 [11]

So, I'm going to have you close your eyes and I'm going to tell you about a patient. She has high blood pressure, abnormal cholesterol, high blood sugar, and she's on a growing list of medications to treat these conditions. She's tired during the day because of her sleep apnea at night. And she cannot even walk up a flight of stairs without stopping to rest. Now open your eyes. She's 9 years old. For the first time in history, we are raising a generation of children that have a shorter life expectancy than ...

Core Insights - The United States has significant shortcomings in public health indicators compared to other wealthy, highly developed countries [1] Health Statistics - The adult obesity rate in the U.S. reached nearly 43% in 2022, which is higher than most high-income countries [1] - The report highlights that only a few high-income countries have a higher obesity rate than the U.S. [1]

Salus Populi Suprema Lex Exto. Il welfare dei cittadini è la legge suprema. Questa è l'iscrizione che trovate in giro per gli edifici pubblici di tutto il mondo ed è forse la regola principale.La nostra salute è la legge suprema. Per la prima volta su questo pianeta ci sono sei generazioni che vivono insieme. Cinque di queste votano insieme, vanno a bere il caffè insieme, si trovano nei barsi nel 2050 ci saranno 2 miliardi di persone over 60 su questo pianeta.Non era mai successo prima. E questo è un argome ...

So, the deadline for Americans who want to sign up for health insurance for January 1st, um, under the Affordable Care Act, um, that deadline is midnight tonight, less than three hours from now, because of what Trump and the Republicans did this year, because they decided to cut off the subsidies that support that health insurance program, 22 million Americans who get their health care from the ACA are about to see dramatic increases in what the premiums will cost. And I mean dramatic increases. the average ...

Sanitation & Human Dignity - Access to proper sanitation, including toilets, is a fundamental human right, essential for maintaining dignity and health [3][4][5] - South Africa's history of inequality has resulted in unequal access to basic sanitation facilities in many communities [6] - Communities are taking charge, transforming sanitation into a space of dignity, action, and change [9] Infrastructure & Urban Planning - Toilets are a critical part of urban infrastructure, essential for healthy, livable, and functional cities [13] - High-density cities require safe and effective waste removal systems [12] - Plumbers play a vital role in maintaining the health of cities by ensuring proper sanitation [9][21] Community-Based Solutions - Community-based solutions, like those implemented by WSAP in Dipsoot, can effectively address sanitation challenges, even without consistent government support [15] - Active citizenship and community involvement are key to improving sanitation and bringing dignity to residents [21][25] - WSAP has demonstrated that cyclical maintenance reduces costs and using quality products leads to long-term savings [15] Water Conservation & Cost Savings - Regular maintenance of toilets can save significant amounts of water, with WSAP saving 4,000 liters per day per toilet [20] - In Dips extension one, WSAP saved 2 million liters of water annually through toilet maintenance [20] - Lack of access to water and sanitation costs 18 African countries $55 billion (550 亿) annually due to health costs, time loss, and productivity costs [17] Global Collaboration & Innovation - International collaborations, such as the International Community Plumbing Challenge, promote innovation and improve sanitation in communities [23] - Plumbing trade competitions, like World Skills, support trades and highlight their importance to economies and city health [22][23] - Plumbers worldwide are actively involved in projects that improve sanitation and promote healthy cities [21] Data & Quantification - In Dips extension one, there are 642 toilets for 25,000 registered residents, equating to 39 households per toilet [10] - Housing for Health, an Australian program, reduced hospital intake by 40% for environmental-related health issues by repairing household environments, including bathrooms and sanitation [17]

Tonight, officials across the country saying the spread of measles is now accelerating. Outbreaks forcing students to go into quarantine and some of them for a second time. Our Emily Aetta joins us now live.And Emily, one of the most serious outbreaks is in South Carolina. >> Yeah, that's right, Tom. Alarm is growing over mounting measles infections in the thick of the holiday season as South Carolina reports more than two dozen new cases just since Friday.The state's epidemiologist today blaming recent gat ...

A group of CDC advisers is weighing some major policy changes to childhood vaccines. The panel is set to meet tomorrow and Friday to discuss whether to scrap the recommendation that newborns should receive hepatitis B vaccinations. >> Now, the vaccine has been credited with significantly preventing the spread of hepatitis B, but skeptics are questioning whether the benefits of the shot actually outweigh the potential health risks.NBC News medical reporter Dr. . Ashal joins us now. Dr. . Dr.. Sel, let's firs ...

Drinking is a way of life in Ireland. Can a warning label change that? https://t.co/1bo6j1E0Al ...

Problem Statement & Current Situation - Each person produces human waste daily, often flushed away and forgotten, initiating a cycle with significant environmental and health consequences [1][2] - Cities face water stress, yet 6-10 liters of fresh water are used per flush [3][4] - Every gram of feces contains approximately 100 billion bacteria, contributing to the spread of diseases like cholera, typhoid, and diarrhea [4][5] - In the country, about 70% of waste goes into the environment without treatment [6] - Only 30% of urban India is connected to sewer systems, and only 28% of the waste gets treated [13] - Septic tanks, while intended as a solution, often lead to untreated waste contaminating water bodies and land [14][15] Proposed Solutions & Innovations - The industry proposes a circular sanitation solution involving on-site treatment to eliminate pathogens, recycle water for agriculture, and use solid waste for soil conditioning [16][17] - Fecal sludge treatment parks utilize pyrolysis to treat waste in under an hour, producing pathogen-free biochar for agriculture and recycling liquid [18][19] - An alternative solution involves a commode-based treatment system using only 1 liter of water, recycling the water for flushing, and using urine to compensate for evaporation [22] - The industry is shifting from a network-based sanitation system to a non-network system, similar to the evolution of mobile phones [25][26] Call to Action & Future Vision - The industry advocates for abandoning the "flush and forget" model in favor of a "flush, treat, and reflush" approach [27] - Collaboration between parliamentarians, governments, and the public is crucial for adopting circular sanitation solutions [27][28] - The industry envisions a future with off-grid toilets, eliminating sewer pipelines, wastewater, and polluted rivers [29][30]