targeted protein degradation (TPD)

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Kymera Therapeutics to Report Second Quarter 2025 Financial Results on August 11, 2025
Globenewswire· 2025-08-04 11:00
WATERTOWN, Mass., Aug. 04, 2025 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing a new class of oral small molecule degrader medicines for immunological diseases, will report second quarter 2025 financial results on August 11, 2025. The Company will host a video conference call and webcast at 8:30 a.m. ET that day. Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines ...
Kymera Surges 70% in 3 Months: Buy, Sell or Hold the Stock?
ZACKS· 2025-07-18 14:56
Core Insights - Kymera's shares have surged 70.7% over the past three months, significantly outperforming the industry gain of 9.7% and the broader S&P 500 index [1][9] - The company is focused on targeted protein degradation (TPD) to develop drugs for various immunological diseases [1] Collaboration with Gilead - Kymera has entered an exclusive option and license agreement with Gilead Sciences to advance a novel molecular glue degrader (MGD) program targeting cyclin-dependent kinase 2 (CDK2), which has potential applications in oncology [4][5] - Under the agreement, Kymera will receive an upfront payment of $85 million, with total potential payments reaching up to $750 million [6] - Kymera may also earn tiered royalties on net product sales, while it will lead research activities for the CDK2 program [7] Setback with Sanofi - Kymera faced a setback with Sanofi, which decided to prioritize the development of a different candidate, KT-485, over Kymera's KT-474, impacting potential milestone payments [10][14] - Despite this, Kymera achieved a $20 million milestone related to preclinical activities for KT-485, which is expected to enter early-stage testing next year [12][13] Pipeline Developments - Kymera's pipeline includes ongoing studies for KT-621 in atopic dermatitis and plans for two phase IIb studies in asthma and atopic dermatitis in late 2025 and early 2026 [15] - The company has identified KT-579 as its lead development candidate, with plans to advance it into phase I testing in early 2026 [16]
Kymera Therapeutics to Unveil New Oral Immunology Program and Report First Quarter 2025 Financial Results on May 9, 2025
Globenewswire· 2025-04-24 11:00
Core Insights - Kymera Therapeutics, Inc. is set to host a video webcast on May 9, 2025, to report its first quarter 2025 financial results and introduce a new oral development candidate targeting autoimmune and rheumatic diseases [1] - The company will also review highlights and upcoming milestones in its immunology pipeline, which is considered industry-leading [1] Company Overview - Kymera Therapeutics is a clinical-stage biotechnology company focused on targeted protein degradation (TPD) to develop innovative medicines for significant health issues [3] - The company aims to create a pipeline of oral small molecule degraders that offer convenient and effective therapies for patients with immunological diseases [3] - Founded in 2016, Kymera has been recognized as one of Boston's top workplaces in recent years [3] Communication and Information Availability - Investors and the public can access information about Kymera through its website, including corporate disclosures, investor presentations, and SEC filings [4] - The company encourages regular review of the information posted on its website and social media platforms [4]