Core Viewpoint - BioSig Technologies, Inc. has signed a definitive share exchange agreement with Streamex Exchange Corporation, marking a significant milestone in the business combination aimed at enhancing the tokenization of real-world assets, particularly in the commodities sector [1][2]. Company Overview - BioSig Technologies is a medical technology company focused on innovative solutions, while Streamex specializes in the tokenization of real-world assets, particularly commodities [1][7]. - The combined entity will be led by Henry McPhie, Co-Founder and CEO of Streamex, with Anthony Amato transitioning to a board role [5]. Transaction Highlights - The share exchange will result in Streamex becoming a wholly owned subsidiary of BioSig, with existing Streamex shareholders entitled to receive 75% of the fully diluted BioSig common stock post-transaction [5][12]. - The transaction is expected to unlock new value in the US$142.85 trillion global commodity market by bringing commodities on-chain through secure tokenization solutions [5][13]. Strategic Additions - Notable strategic advisors have joined the combined company, including Frank Giustra, Mathew August, and Mitchell Williams, bringing extensive experience in commodities and capital markets [6]. Market Positioning - Streamex aims to revolutionize commodity finance by bridging traditional finance with the digital economy, enhancing liquidity, accessibility, and efficiency through innovative financial technologies and blockchain [8].

Core Viewpoint - Medtronic plc will participate in Bernstein's 41st Strategic Decisions Conference on May 29, 2025, where CEO Geoff Martha will present and answer questions alongside CFO Thierry Piéton [1][2]. Company Overview - Medtronic is a leading global healthcare technology company headquartered in Galway, Ireland, with a mission to alleviate pain, restore health, and extend life [4]. - The company employs over 95,000 people across more than 150 countries and addresses 70 health conditions through various technologies and therapies, including cardiac devices, surgical robotics, and patient monitoring systems [4]. - Medtronic aims to deliver innovative technologies that transform lives, impacting two people every second [4]. Event Details - The presentation by CEO Geoff Martha will begin at 11:00 a.m. EDT on May 29, 2025, followed by a Q&A session with CFO Thierry Piéton [2]. - A live webcast of the event will be available on Medtronic's investor relations website, with an archive accessible later the same day [3].

At the EuroPCR 2025, Edwards Lifesciences (EW) has announced new economic and clinical evidence on severe aortic stenosis (AS). The results of a new real-world study, comprising more than 24,000 patients, demonstrated that intervening on the disease before symptoms develop reduces the economic and resource burden on the healthcare system and improves patient outcomes.Presented as a late-breaking clinical trial, the data further contributes to the extensive body of research on this disease. The development i ...

MALVERN, Pa., May 22, 2025 (GLOBE NEWSWIRE) -- TELA Bio, Inc. (NASDAQ: TELA), a commercial-stage medical technology company focused on providing innovative soft-tissue reconstruction solutions, today announced that the Company will participate in the 2025 Jefferies Global Healthcare Conference. TELA’s management is scheduled to present at the 2025 Jefferies Global Healthcare Conference at 11:05 am ET on June 5th, 2025. Interested parties can access the live and archived webcast at ir.telabio.com. About TELA ...

Autonomix Medical, Inc. (AMIX) recently announced that it has been granted a key U.S. patent for its innovative catheter-based platform designed to sense and differentiate nerve signals in real-time. This technology represents a significant leap forward in the field of neuromodulation, with the potential to enhance treatment precision across a wide range of chronic conditions, including cancer and pain management. The platform enables both sensing and stimulation of nerves through a single device.With the b ...

Play Audio Read more: Nipro: New Mid-term Plan: Will Nipro Achieve Dynamic Capex Allocation? (20 May 2025) May 21, 2025 02:00 AM GMT Sound Bites | Japan M Update Nipro: New Mid-term Plan: Will Nipro Achieve Dynamic Capex Allocation? Industry View In-Line The capex plan is our particular focus among the many KPIs. Although management has rejigged the balance of capex among businesses, we think investors may have preferred a plan for an overall clear capex reduction. Morgan Stanley MUFG Securities Co., Ltd.+ ...

Core Viewpoint - Glaukos Corporation is positioned for growth due to favorable clinical trial results and a strong product pipeline, despite facing significant competition [1] Company Overview - Glaukos has a market capitalization of $5.48 billion and is recognized as a leading ophthalmic medical technology and pharmaceutical company, with a trailing four-quarter average earnings surprise of 21.62% [2] Key Catalysts - Strong product demand is primarily driven by the success of the flagship product, iStent, which has led to a robust performance in 2024 and a positive business outlook [3] - The adoption of iStent Infinite for glaucoma patients is increasing, supported by enhanced clinical education and improved market access, with five out of seven Medicare Administrative Contractors releasing draft local coverage determinations [4] Financial Performance - Glaukos' revenues exceeded estimates in Q1 2025, improving by 24.6% year over year, with expectations for full-year 2025 revenues between $475 million and $485 million, reflecting a projected sales growth of 25.5% and earnings growth of 53.4% [5] Product Portfolio Expansion - The first quarter's top line was significantly boosted by the strong adoption of the iDose TR product, with the U.S. glaucoma segment experiencing 41% year-over-year growth [6] - The FDA has accepted the NDA for Epioxa, a next-generation therapy for keratoconus, with a PDUFA date set for October 2025 [7] International Growth - Glaukos is expanding its international presence, reporting record sales of $29 million in its international glaucoma franchise for Q1, reflecting an 18.7% year-over-year operational growth [10] Challenges - The company relies on a limited number of third-party suppliers for components, which poses a risk if suppliers fail to deliver [11] - Restrictive Medicare Local Coverage Determinations have negatively impacted the U.S. stent business, leading to a mid-single-digit decline despite growth in iDose [12] Estimate Trends - The bottom-line estimate for Glaukos is a loss of 87 cents for 2025, which has narrowed by 8.4% in the past 30 days, with the Zacks Consensus Estimate for 2025 revenues at $480 million [13]

Core Viewpoint - The Beauty Health Company has announced a refinancing initiative aimed at strengthening its financial position and extending the maturity of a portion of its existing debt, which will facilitate long-term growth investments [2]. Group 1: Refinancing Details - The company has entered into exchange agreements to swap approximately $413.2 million of existing 1.25% convertible senior notes due 2026 for $250.0 million of new 7.95% convertible senior secured notes due 2028, along with approximately $143.4 million in cash [2]. - The new notes will be senior, secured obligations guaranteed by certain subsidiaries and will bear an interest rate of 7.95% per annum [2]. - The initial conversion rate for the new notes is set at 349.6503 shares per $1,000 principal amount, translating to a conversion price of approximately $2.86 per share [2]. Group 2: Strategic Focus - The CEO emphasized that the refinancing is a critical step in enhancing the company's financial flexibility, allowing for investments in innovation and brand initiatives [2]. - The company aims to improve commercial execution, accelerate product development, and deepen engagement with providers [2]. Group 3: Transaction Advisors - Goldman Sachs is serving as the exclusive financial advisor for the transaction, while Latham & Watkins LLP is acting as transaction counsel [3].

Core Insights - The studies published in The Lancet Oncology and Cancer Medicine reveal that cancer patients are at a significantly higher risk of developing antimicrobial resistant (AMR) infections compared to non-cancer patients, highlighting the urgent need for improved infection control measures in this vulnerable population [1][2][4]. Study Findings - The studies are the first large, multi-center investigations quantifying AMR among cancer patients in the U.S., providing strong evidence that superbugs pose a substantial risk across various healthcare settings [2][6]. - AMR rates among key pathogens were found to be 1 to 3 times higher in outpatient cancer patients, with some specific pathogen-source combinations showing up to 5 times greater rates compared to non-cancer patients [6][8]. - Hospitalized cancer patients were found to be 1.5 to 2 times more likely to encounter AMR infections than their non-cancer counterparts [6][8]. Implications for Cancer Care - The emergence of AMR threatens the effectiveness of antibiotics, which are crucial for treating infections and preventing complications during cancer treatments such as chemotherapy and surgery [3][4]. - The findings suggest that the rapid rise of AMR could undermine new cancer therapies, including CAR T-cell therapy and other immunotherapies, due to the associated risks of immunosuppression and opportunistic infections [3][4]. Recommendations - The studies emphasize the need for enhanced infection prevention programs, focused antibiotic stewardship, and the increased use of rapid diagnostic tools to better manage AMR risks in cancer patients [4][6].

Core Insights - Penumbra, Inc. is scheduled to present at multiple investor conferences in June 2025, showcasing its commitment to engaging with investors and stakeholders [1][2]. Group 1: Upcoming Events - The company will present at the William Blair 45th Annual Growth Stock Conference on June 3, 2025, at 3:00 PM ET [2]. - The Jefferies Global Healthcare Conference is scheduled for June 4, 2025, at 9:55 AM ET [2]. - The Truist Securities MedTech Conference will take place on June 17, 2025, at 10:00 AM ET [2]. Group 2: Company Overview - Penumbra, Inc. is recognized as the world's leading thrombectomy company, focusing on innovative technologies for medical conditions like ischemic stroke and venous thromboembolism [3]. - The company's portfolio includes computer-assisted vacuum thrombectomy (CAVT), aimed at efficiently removing blood clots [3]. - Penumbra operates in over 100 countries, supporting healthcare providers to enhance patient outcomes and quality of life [3].