Core Viewpoint - A team from Beihang University has developed a flexible implantable bioelectronic device called POCKET, which allows for personalized drug delivery and gene transfection, addressing challenges in treating hereditary ovarian gene mutations [1][2]. Group 1: Technology Development - The POCKET device utilizes electroporation, a physical method that opens cell membranes by applying an electric field, enabling efficient drug delivery [2]. - Traditional electroporation devices struggled with conforming to the irregular surfaces of organs, leading to poor delivery efficiency. The team introduced a "customized paper-cutting conformal theory" to create a device that fits organ surfaces precisely [2]. Group 2: Applications and Validation - The POCKET device has been validated in various animal models and human tissues, showing potential for precise treatment of ovarian cancer prevention and organ damage repair [2]. - The technology can be expanded to treat diseases and facilitate regeneration in other organs such as the liver, heart, and lungs, representing a new paradigm in bioelectronic medicine [2]. Group 3: Commercialization and Future Prospects - A high-tech company based on this technology has completed multiple rounds of financing, with the first product, "Ultra-NEP," already applied in skin health [2]. - Future plans include expanding applications in medical-grade devices, indicating a strong potential for growth in the healthcare technology sector [2].