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细胞治疗设备制造
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打破“高价壁垒”,“济南造”助力细胞治疗“大众可及”
Qi Lu Wan Bao Wang· 2025-08-01 07:20
Core Viewpoint - The conference highlighted the introduction of automated equipment by Pansheng Group aimed at reducing the high costs associated with cell therapy, making it more accessible to the general public [1][3]. Group 1: Technology and Innovation - Pansheng Group's automated cell production and storage management platform utilizes a combination of "fully enclosed isolators, six-axis robots, and AI visual recognition" to achieve a fully automated process for cell separation, activation, transduction, amplification, and formulation [5]. - The equipment can handle up to 10 billion cells per batch and operates 24 hours unattended, supporting the treatment needs of 5,000 patients annually, which is 8-10 times the capacity of manual production [5]. - The quality incident rate of the automated system is reduced to 0.2‰, significantly lower than the industry average of 1/20 [5]. Group 2: Economic Impact and Accessibility - The system is designed with principles of "unmanned, intelligent, standardized, and high-throughput" to dismantle cost structures, making cell therapy potentially more affordable for the public [5]. - Pansheng Group is establishing three "cell manufacturing centers" in regions like Jinan High-tech Zone, all connected to a central control room for coordinated and flexible production expansion [5]. - The company is also implementing financial models such as equipment leasing and on-demand production fees to alleviate financial pressures on pharmaceutical manufacturers, enhancing R&D efficiency and reducing marginal costs [5]. Group 3: Future Outlook - The high price barrier of cell therapy is seen as surmountable through systematic, industrialized, and standardized approaches to reconstruct the industry chain [5]. - With the approval of multi-indication drugs and comprehensive involvement of commercial insurance, cell therapy is expected to become more accessible to the general public [5].
产线利用率从35%提升到85%,“济南造”细胞设备带来新变革
Qi Lu Wan Bao Wang· 2025-08-01 07:04
Group 1 - The core viewpoint of the news is the introduction of the automated equipment for the dual intelligent cell production and storage management platform by Pansheng Bioengineering Group, which aims to enhance the efficiency and quality of cell therapy production [1] - Pansheng Group has invested 680 million yuan over five years to develop this automated system, which can switch between eight process routes for various therapies, significantly increasing production line utilization from 35% to 85% and reducing fixed costs by over 40% [1] - The automated preparation system incorporates over 1,000 process parameter models and 210 regulatory knowledge maps, allowing ordinary technicians to be trained in just two weeks, resulting in a sixfold increase in output per person and a 70% reduction in labor costs [1] Group 2 - The automated equipment utilizes a fully enclosed isolator, six-axis robots, and AI visual recognition to perform the entire cell processing workflow without human intervention, achieving a processing capacity of up to 10 billion cells per batch and supporting the treatment needs of 5,000 patients annually [2] - The quality incident rate of the automated system is reduced to 0.2‰, which is only 1/20th of the industry average, indicating a significant improvement in quality control compared to manual operations [2]