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基因编辑技术让家蚕性别由雌变雄
Ke Ji Ri Bao· 2025-07-15 00:59
Core Viewpoint - The research conducted by Professor Tong Xiaoling's team at Southwest University successfully achieved the sex reversal of silkworms from female to male using gene editing technology, marking a significant breakthrough in insect breeding and pest control strategies [1][2]. Group 1: Research Breakthrough - The study utilized CRISPR/Cas9 gene editing technology to target the key gene Bmdsx, which controls the sex determination in silkworms, leading to the forced skipping of specific exons that resulted in the development of male characteristics in previously female silkworms [2]. - The edited female silkworms exhibited male-specific traits, including an eight-segmented abdomen and male reproductive organs, capable of producing sperm similar to male silkworms [2]. Group 2: Implications for Industry - This breakthrough is expected to facilitate the breeding of higher yield and quality silkworm varieties, thereby promoting the development of the silk industry [2]. - The findings also have broader applications, as similar sex determination mechanisms were identified in various pests, including mosquitoes and cotton bollworms, providing a theoretical basis for developing new pest control strategies and ensuring sustainable agricultural production [2].