Core Insights - The search for profitable stocks in San Francisco revealed unexpected results, with a focus on biotech and other sectors rather than solely A.I. related companies [1][2] Company Performance - Nektar Therapeutics (NKTR) is the top performer, with a 150% increase in the past 90 days, focusing on treatments for dermatitis and Alopecia areata, with a bullish price target of $93.60 from analysts [5] - Sunrun (RUN), a solar power company, has doubled in value over three months, experiencing significant volatility, with shares fluctuating from $6 to above $20 [6] - The RealReal (REAL), a resale company for luxury items, is trading slightly above the median price target set by analysts, indicating potential caution for investors [7] - Planet Labs (PL), an 'earth intelligence' company, has seen its stock nearly double in a year, with sales more than doubling over the last four years, though it has experienced volatility [8] - Other notable companies include Fastly (FSLY), Maze Therapeutics (MAZE), Olema Pharmaceuticals (OLMA), Septerna (SEPN), and Cytokinetics (CYTK), all of which have performed well recently, particularly in the biotech sector [9]