Core Viewpoint - The article discusses the innovative biological control method of using sterilized male mosquitoes to combat mosquito-borne diseases, particularly focusing on the efforts in Guangdong, China, to address the spread of the Chikungunya virus through the establishment of a "mosquito factory" that breeds millions of sterilized male mosquitoes weekly [1][4][11]. Group 1: Biological Control Methods - The Guangdong region is implementing biological control methods, including the "mosquito control by mosquitoes" strategy, to combat the Chikungunya virus, which has seen an increase in cases since July [2][4]. - The "mosquito factory" in Guangzhou, operated by Guangzhou Weibai Kun Biotechnology Co., breeds 5 million sterilized male mosquitoes weekly, which are released to mate with wild female mosquitoes, resulting in non-viable eggs [5][7]. Group 2: Production and Release Strategy - The mosquito factory employs advanced technology, including automated sorting and separation of mosquito larvae, achieving a male mosquito production accuracy of less than 0.3% [5][7]. - The release strategy involves a ratio of more than 5:1, meaning for every wild female mosquito found, over five sterilized males are released to ensure effective mating [7]. Group 3: Efficacy and Results - Monitoring data indicates that the introduction of sterilized male mosquitoes leads to a rapid stabilization of mosquito populations within 5 to 10 minutes, with a potential reduction of mosquito numbers by 50% within three weeks and over 80% within six to eight weeks [7][9]. - The use of Wolbachia bacteria in mosquitoes has shown promise in reducing the transmission of diseases like dengue and Zika, with successful trials reported in Brazil leading to significant decreases in disease cases [9][10]. Group 4: Global Collaboration and Expansion - The company is collaborating with Mexico to establish a similar mosquito factory model aimed at controlling dengue fever, and Singapore has also adopted this technology with reported effectiveness in reducing dengue cases by over 70% [10]. - The World Health Organization has raised alarms about the global spread of the Chikungunya virus, highlighting the urgency of such biological control measures as 119 countries have reported cases, affecting approximately 5.5 million people [11].

Core Viewpoint - The key to controlling Chikungunya fever lies in mosquito prevention and extermination through innovative biological methods [1][2] Group 1: Company Overview - Guangzhou Weibai Kun Biological Technology Co., Ltd. operates a facility in Huangpu District, Guangzhou, known as the "mosquito factory" [1] - The company currently produces 5 million "sterile male mosquitoes" weekly, utilizing a biological technique to disrupt the mosquito breeding chain [1] Group 2: Technology and Methodology - The "mosquito control" strategy focuses on reducing the population of Aedes mosquitoes, leveraging the symbiotic relationship between Wolbachia bacteria and mosquito vectors [1] - The produced mosquitoes are termed "beneficial mosquitoes" or "sterile male mosquitoes," which, when mating with wild female mosquitoes, result in non-viable eggs due to cytoplasmic incompatibility [1] Group 3: Advantages and Safety - The "mosquito control" technology is noted for its high efficiency, low biological safety risks, and environmentally friendly characteristics, with a key feature being its precision targeting [1] - The released male mosquitoes do not bite humans, thus not increasing the risk of mosquito bites [1] Group 4: Future Plans - Since 2015, the company's "mosquito control" technology has been tested in various regions across the country, yielding impressive results [2] - The company plans to collaborate with grassroots organizations for ongoing mosquito prevention efforts and aims to institutionalize the "mosquito control" initiative [2]

Core Viewpoint - The article highlights the innovative "mosquito factory" in Guangzhou, which produces sterilized male mosquitoes to combat the spread of the chikungunya virus through biological control methods, representing a significant advancement in pest management technology [1][4]. Group 1: Technology and Methodology - The "mosquito factory" produces 5 million sterilized male mosquitoes weekly, utilizing a biological technique to disrupt the breeding cycle of the Aedes albopictus mosquito, which is responsible for transmitting chikungunya and dengue fever [1][4]. - The technology involves breeding male mosquitoes that carry the Wolbachia bacteria, which, when mated with wild female mosquitoes, results in non-viable eggs, effectively reducing the mosquito population over time [2][3]. - The precision of the method is notable, with an error rate of less than 0.5% in sorting mosquito larvae and less than 0.3% in the emergence of male mosquitoes, ensuring high efficiency in the breeding process [2]. Group 2: Effectiveness and Results - The "mosquito control" strategy has shown significant results, with a reported 90% control rate of Aedes albopictus in trial areas, and no dengue fever cases reported in the last seven years in the tested regions [3]. - The method can reduce mosquito populations by 50% within three weeks and achieve an 80% reduction in wild mosquito density within 6 to 8 weeks of implementation [3]. - The company plans to continue its efforts in mosquito control and collaborate with local organizations to maintain ongoing pest management strategies [4].