Core Viewpoint - A recent study published in the journal Nature Medicine indicates that approximately 15.6 million individuals born globally between 2008 and 2017 are expected to be diagnosed with stomach cancer in their lifetime, with 11.9 million cases (76%) linked to Helicobacter pylori infection [1][2] Group 1: Cancer Statistics - Stomach cancer is the fifth leading cause of cancer-related deaths globally, primarily caused by chronic infection with Helicobacter pylori, which is preventable through effective treatment [1] - The study predicts that 10.6 million new stomach cancer cases will occur in Asia, while sub-Saharan Africa, currently with a lower burden, is expected to see its burden increase to at least six times the 2022 estimates [2] Group 2: Prevention and Screening - The authors of the study advocate for increased investment in stomach cancer prevention, particularly through population-wide screening and treatment programs for Helicobacter pylori to reduce the global burden of stomach cancer [1] - The research suggests that implementing screening and treatment strategies could potentially reduce the predicted number of stomach cancer cases by up to 75% [2] Group 3: Data Limitations - The predictions made in the study are subject to limitations in data quality and coverage, especially in resource-poor areas where cancer registries may be incomplete or missing [2]