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靶向RNA小分子创新药物
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砺博生物宣布完成近亿元Pre-A轮融资
Group 1 - The core viewpoint of the news is that Libo Biotech has successfully completed nearly 100 million yuan in Pre-A round financing, which will accelerate its development in the targeted RNA small molecule drug sector [1][2][3] - The financing was led by Tianshili Capital and Panlin Capital, with participation from Yuan Sheng Venture Capital, Zhejiang Province's "4+1" Biopharmaceutical and High-end Equipment Industry Fund, and Chengxin Venture Capital [1] - Libo Biotech was founded in September 2022 and has already secured angel investment from Innovation Works and Sequoia China in November of the same year [1] Group 2 - The company has developed an AI-enabled target discovery platform that overcomes traditional RNA secondary structure detection limitations, allowing for the identification of stable folded RNA tertiary structures with potential small molecule binding pockets [2] - Libo Biotech has established a comprehensive platform for screening, optimizing, and validating targeted RNA small molecules, supported by AI models that enable rapid discovery and optimization of small molecule drugs [2] - The company is advancing pipelines in central nervous system disorders, cancer, and autoimmune diseases, aiming to translate cutting-edge technology into clinical breakthroughs [2][3] Group 3 - The founder, Dr. Jian Zhan, expressed gratitude for the support from shareholders and emphasized the belief that stable tertiary structures in RNA are optimal targets for small molecule drugs, holding the key to disruptive therapies [3] - Tianshili Capital's partner, Tan Chongli, highlighted the global innovation of Libo Biotech in the targeted RNA drug development field and noted the challenges in this area, stating that targeting stable tertiary structures has high druggability [3] - The integration of AI in drug development is a key focus for Tianshili Capital, as it aims to enhance the efficiency and success rate of developing RNA small molecule drugs [3]