Key Points AMD stock rose 77.3% in 2025, nearly doubling the S&P 500's return and outpacing Nvidia in the last three months. OpenAI signed a multi-year deal to buy 6 gigawatts of AMD Instinct AI accelerators, representing a $120 billion revenue opportunity over the next 5 years. The deal signals that AMD can compete with Nvidia for high-end AI workloads. 10 stocks we like better than Advanced Micro Devices › Shares of AMD (NASDAQ: AMD) rose 77.3% in 2025, according to data from S&P Global Market ...