Core Insights - Grayscale has submitted an S-1 registration statement to the U.S. Securities and Exchange Commission to launch ETFs for Polkadot (DOT) and Cardano (ADA) [1] - This submission is a follow-up to Grayscale's previously filed 19b-4 forms, indicating the company's ongoing efforts to advance its product listing process [1] - The move is part of Grayscale's regular filing procedures and is not a new application [1]