Financial Data and Key Metrics Changes - In 2025, Mirion Technologies booked record orders totaling more than $1 billion, representing a 26% increase compared to 2024 [4][8] - Full year revenue totaled $925.4 million, up 7.5% versus 2024, with more than half of the growth being organic [23] - Adjusted EBITDA for the full year was $227.9 million, up 12% compared to 2024, with margins expanding by 90 basis points [23][27] - Adjusted EPS for the full year was $0.46, a 12% increase despite an increase in diluted shares [24] Business Line Data and Key Metrics Changes - Nuclear power organic revenue grew more than 11% in 2025, while nuclear medicine organic revenue grew more than 13% [4] - The medical segment revenue declined 3.5% in Q4 2025, but full year medical segment revenue grew 3.7% [28] - The nuclear and safety segment revenue for Q4 was $194.9 million, up 15.5%, with organic revenue increasing 3.1% [25] Market Data and Key Metrics Changes - The nuclear power end market demonstrated the strongest growth, supported by $150 million from the large opportunity pipeline [8] - The defense and diversified end market saw a doubling of orders in Q4, primarily in the U.S. and with NATO [22] - Medical segment orders faced headwinds due to tough comps from the prior year, with nuclear medicine orders down only 6% in 2025 [9] Company Strategy and Development Direction - The company articulated a strategic priority to increase nuclear power exposure, acquiring Sertrek and Paragon Energy Solutions to augment its North American nuclear power presence [5][12] - The focus is on broadening exposure to dynamic verticals and enhancing customer intimacy through acquisitions [12] - The company expects to leverage AI for both customer-facing applications and internal productivity improvements [59][63] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the nuclear power sector, citing a robust demand for solutions due to a shortage in generating capacity in developed markets [6] - The company anticipates double-digit organic growth in nuclear power for 2026, supported by a growing opportunity pipeline [6][20] - Management noted that headwinds in 2025 were seen as demand deferrals rather than a secular change in the market [10] Other Important Information - Adjusted free cash flow for 2025 totaled $131 million, approximately double that of 2024, with a 57% conversion rate [30] - The company expects 2026 total revenue growth between 22%-24%, with organic revenue growth guidance of 5%-7% [16][17] Q&A Session Summary Question: Can the large opportunity pipeline translate to double-digit growth in backlog for 2026? - Management noted that while large project timing is complex, they feel good about the underlying dynamics driving growth in the nuclear power vertical [36][39] Question: What is expected for medical segment growth in 2026? - Management indicated that they expect mid-single-digit growth in the medical segment, with a stronger performance anticipated in the second half of the year [40][41] Question: How does the Paragon acquisition impact margins and growth? - Management expects Paragon to contribute positively to margins over time, with significant growth anticipated in 2026 [65][66] Question: What is the expected contribution from large orders booked in 2025 to 2026 revenue? - Management indicated that while there will be some contribution, the first year of larger contracts tends to be the lightest [74] Question: How material are SMRs to Mirion's growth story? - Management noted that while SMRs currently represent a small percentage of total revenue, they are excited about the growth potential and ongoing engagement with SMR developers [75][76]

Group 1 - Danaher Corporation (NYSE:DHR) has been highlighted by Jim Cramer as a stock with potential upside, particularly in the healthcare sector, despite its recent performance being disappointing [1][2] - The stock experienced a notable increase of more than 7% recently, indicating a possible recovery trend in the healthcare market [1] - Danaher develops a range of products in medical, life sciences, biotechnology, and diagnostics, including bioprocessing technologies and clinical instruments [2] Group 2 - Cramer expressed that Danaher has struggled to stabilize since its purchase in early 2022, failing to find its footing in the market [2] - There is a belief that certain AI stocks may offer greater upside potential compared to Danaher, suggesting a competitive landscape for investment opportunities [2]

Core Insights - Danaher Corporation (NYSE:DHR) is considered one of the best medical stocks to buy currently, despite a recent price target reduction by BofA from $230 to $220 while maintaining a Buy rating [1] - There are signs of stabilization and improvement in certain areas of Life Sciences and Diagnostic Tools, but there are also pockets of uncertainty and softness observed over the past year [2] - BofA anticipates that these trends will continue for at least the next few quarters, leading to a more gradual return to normalcy in the market [2] Company Overview - Danaher Corporation designs, manufactures, and markets a wide range of professional, medical, industrial, and commercial products and services, making it a significant player in the diagnostics sector [2] - The company operates through several segments, including Diagnostics, Biotechnology, Life Sciences, and Environmental and Applied Solutions [2] Segment Details - The Biotechnology segment provides various equipment and consumables for biological medicines [3] - The Life Diagnostics segment offers clinical instruments, devices, consumables, and services for diagnosing and treating diseases [3]