Core Viewpoint - The article explores the historical development and breakthroughs in China's liquid chromatography industry, highlighting the contributions of key figures and the evolution of technology from its inception to the present day, emphasizing the importance of innovation and resilience in overcoming challenges [1][4][40]. Group 1: Historical Development - Liquid chromatography has evolved significantly since its inception in 1903, with the first commercial high-performance liquid chromatography (HPLC) instrument emerging in the late 1960s, marking its entry into laboratories [4][10]. - The first Chinese volume chromatography instrument was designed by Lu Peizhang in 1953, reducing the analysis time for petroleum samples from 30 hours to 1 hour, which was crucial for the development of the national industry [9][10]. - The establishment of the liquid chromatography discipline in China was marked by Lu Peizhang's presentation of the first gas chromatography report in 1956 [9][10]. Group 2: Key Figures and Their Contributions - Lu Peizhang, a pivotal figure in Chinese liquid chromatography, faced significant challenges in the 1950s due to a lack of resources and knowledge, yet he persevered to lay the foundation for the field [9][12]. - Zhang Yu-kui, a disciple of Lu Peizhang, embraced cutting-edge research and technology, contributing to the development of software for chromatographic analysis and becoming one of the first scientists in China to master programming [15][18]. - Li Tong, the founder of Yilit, was influenced by the teachings of Lu and Zhang, leading to the establishment of a successful liquid chromatography instrument manufacturing company that emphasizes user-centric product development [19][25]. Group 3: Technological Advancements and Market Position - Yilit has launched five generations of liquid chromatography products, with the latest, the EClassical 3200L, achieving recognition for its performance and stability, marking a significant step towards high-end domestic alternatives [29][32]. - The company maintains a commitment to R&D, investing over 10% of its annual sales in technological advancements, ensuring that its products meet the highest standards [27][30]. - The transition of Yilit's headquarters to Suzhou signifies a strategic shift towards high-end technology and international market expansion, aiming to enhance the global perception of Chinese instruments [35][39]. Group 4: Future Outlook and Challenges - The article emphasizes the need for continuous innovation and the adoption of new technologies to overcome international challenges and improve the global standing of Chinese liquid chromatography instruments [35][39]. - The next generation of leaders in the industry, such as Li Yabo, are focused on expanding product lines and deepening collaborations in biopharmaceuticals and clinical fields, indicating a forward-looking approach to growth [39][40]. - The legacy of resilience and innovation established by previous generations is crucial for the ongoing development of China's liquid chromatography sector, as it seeks to challenge established international brands [40][46].

Core Viewpoint - Yilit Technology has established itself as a leader in the domestic liquid chromatography industry with a 95% localization rate and over 18,000 units sold, driving the process of domestic substitution [2][12]. Group 1: Company Development - Yilit Technology, founded over 30 years ago, has consistently maintained its leading position in the liquid chromatography sector through continuous innovation and strategic expansion [2][4]. - The company has recently relocated to a new facility in Suzhou, which has more than doubled its operational space and increased its workforce from 20 to nearly 100 employees, enhancing its production capacity and R&D capabilities [6][10]. Group 2: Technological Advancements - Yilit has achieved a 95% localization rate for core components, establishing a significant technological barrier and ensuring full-chain autonomy from hardware to software [7][9]. - The EClassical 3200L liquid chromatography instrument features self-developed direct drive pump technology, capable of withstanding pressures up to 130 MPa, making it suitable for clinical and pharmaceutical applications [9][12]. Group 3: Market Position and Customer Engagement - The company has sold over 18,000 instruments and more than 200,000 chromatography columns, serving over 15,000 clients across various sectors, including petrochemicals, biomedicine, and food safety [10][11]. - Yilit has developed an online HPLC spectrum library with nearly 1,000 verified spectra, aligning with the latest pharmacopoeia standards to enhance user experience and efficiency in experimental design [10][12]. Group 4: Future Outlook - Yilit plans to continue its focus on technological innovation and ecosystem development, aiming to expand its product offerings and international channels while collaborating with renowned domestic and international enterprises [13].