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Tevogen Updates on Development of EBV-Specific T Cell Therapy with Support from AI-Powered Target Discovery
GlobeNewswire News Room· 2025-06-18 12:30
Core Insights - Tevogen Bio is advancing its development of a cytotoxic T lymphocyte (CTL) therapy targeting Epstein-Barr virus (EBV)-associated lymphomas [1] - The company is utilizing its proprietary ExacTcell™ technology to manufacture EBV-specific CTLs for potential clinical trials [2] - Collaboration with Tevogen.AI aims to enhance peptide selection strategies for identifying immunologically active targets across the EBV genome [3] - The understanding of EBV-induced tumorigenesis has improved, highlighting the potential for CTLs to target EBV proteins for therapeutic breakthroughs [4] Research and Development - Computer-based selection of EBV peptides is in progress as part of preparation for clinical trials [2] - Confirmation studies are being conducted in Tevogen's R&D laboratory to validate CTL responses to selected viral peptides [2] - The collaboration with Tevogen.AI is focused on accelerating the identification of effective immunological targets [3] Scientific Insights - Recent advancements have clarified the mechanisms of EBV-induced tumorigenesis, which involve disruption of cellular pathways and promotion of malignant growth [4] - Targeting EBV proteins with specific CTLs represents a promising area for research and potential therapeutic advancements in EBV-driven cancers [4] Future Directions - Tevogen Bio plans to provide ongoing updates as its EBV research progresses through the preclinical evaluation phase [4]