Core Insights - MaxCyte has signed a strategic platform license agreement with Adicet Bio to utilize its Flow Electroporation® technology and ExPERT™ platform for developing gamma delta T cell therapies [1][2] - Adicet Bio aims to enhance its manufacturing capabilities for allogeneic gamma delta T cell therapies, which are designed for cancer and autoimmune diseases [3][4] Company Overview - MaxCyte is a leading cell-engineering company focused on advancing cell-based therapeutics through its Flow Electroporation® technology and ExPERT™ platform [5] - The company has over 25 years of experience in cell engineering, providing tools and services that support the development of safe and effective treatments [5] Agreement Details - The agreement grants Adicet Bio non-exclusive rights for research, clinical, and commercial use of MaxCyte's technologies, while MaxCyte will receive licensing fees and program-related revenue [2] - MaxCyte's ExPERT™ platform is noted for its high transfection efficiency, cell viability, and scalability, which are essential for developing next-generation cell therapies [4]

Company Overview - MaxCyte supports 19 clinical and commercial therapies and has 29 SPL customers[9] - The company reported $386 million in 2024 revenue with an 84% Non-GAAP adjusted gross margin[10] - MaxCyte has $190 million in cash and cash equivalents as of December 31, 2024[10] Cell and Gene Therapy Market - There are approximately 1,950 active clinical trials focused on cell and gene therapy as of December 2024[14] - The cell and gene therapy field raised an aggregate of $152 billion in 2024[14] - There are 44 approved cell and gene therapies[14] Strategic Platform Licenses (SPLs) - MaxCyte has 29 SPL customers, with 18 programs currently in clinical development and 1 commercial program[47] - These 18 active clinical programs represent over $220 million of pre-commercial milestone potential[47] - SPL Program-Related revenue accounted for 57% of Core revenue[68] Financial Performance - Total core revenue for the full year 2024 was $325 million, a 9% increase year-over-year[69] - Total revenue for the full year 2024 was $386 million, a 6% decrease year-over-year[69] - Non-GAAP adjusted gross margin was 84% for the full year 2024[69]

Core Insights - MaxCyte, Inc. reported a solid start to 2025 with core revenue growth driven by strong performance in Strategic Platform Licenses (SPL) [3] - The company added one new SPL client, TG Therapeutics, in February 2025, bringing the total number of active SPLs to 29 [6][7] - The integration of SeQure Dx is progressing well, presenting substantial long-term opportunities in safety assessment services [3] Financial Performance - Core business revenue for Q1 2025 was $8.2 million, a 1% increase compared to Q1 2024 [6][7] - SPL Program-related revenue decreased to $2.1 million in Q1 2025 from $3.2 million in Q1 2024, marking a 32% decline [6][8] - Total revenue for Q1 2025 was $10.4 million, down 8% from $11.3 million in Q1 2024 [6][7] Profitability Metrics - Gross profit for Q1 2025 was $8.9 million, resulting in a gross margin of 86%, compared to 88% in Q1 2024 [8] - Operating expenses decreased to $21.2 million in Q1 2025 from $22.2 million in Q1 2024 [9] - The net loss for Q1 2025 was $10.3 million, compared to a net loss of $9.5 million in Q1 2024 [10] Cash Position and Guidance - As of March 31, 2025, total cash, cash equivalents, and investments were $174.7 million [6] - The company reiterated its 2025 revenue guidance, expecting core business revenue to grow by 8% to 15% compared to 2024 [11][15] - SPL Program-related revenue is projected to be approximately $5 million for the year [15]