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Esperion Partner Otsuka Receives Regulatory Approval to Market NEXLETOL® in Japan for the Treatment of Hypercholesterolemia
Globenewswire· 2025-09-19 12:00
Core Insights - Esperion has received regulatory approval for NEXLETOL® (bempedoic acid) in Japan, marking a significant milestone in its international growth strategy [1][2] - The approval allows Esperion to expand its global footprint in the cardiovascular prevention market, which is crucial for patients needing non-statin LDL-C lowering therapies [2] - The partnership with Otsuka Pharmaceutical is expected to unlock substantial value in Japan, with Esperion set to receive milestone payments and tiered royalties based on sales performance [2] Company Overview - Esperion Therapeutics is a biopharmaceutical company focused on developing and commercializing oral, once-daily, non-statin medications for patients at risk of cardiovascular disease [3] - The company’s products are supported by the CLEAR Cardiovascular Outcomes Trial involving nearly 14,000 patients, highlighting its commitment to addressing unmet medical needs [3] - Esperion is advancing its pipeline with a focus on developing ATP citrate lyase inhibitors (ACLYi), leveraging new insights for rational drug design [3][4] Market Position - The approval of NEXLETOL in Japan, alongside existing approvals in the U.S. and Europe, positions Esperion as a key player in the global cardiovascular market [2] - The company aims to drive long-term growth and shareholder value through continued innovation and market expansion [2]