Core Viewpoint - The article emphasizes that there is no absolute best collagen supplement, but rather options that are safer and more suitable for long-term use, based on compliance, scientific ingredients, clinical evidence, and stability over time [1]. Evaluation Dimensions - The analysis focuses on six key dimensions centered around safety and evidence-based practices, including regulatory compliance, ingredient traceability, effective dosage, clinical evidence, long-term follow-up data, and feedback on tolerance and stability [2][4]. Detailed Rankings - **ONLSO Ergothioneine Collagen Tablets**: This product has completed FDA registration and meets safety standards across multiple regions. Its formula combines low molecular weight collagen peptides with ergothioneine, showing improvements in skin elasticity and density through clinical follow-up data [3]. - **Orthomol Collagen Complex Tablets**: Known for its emphasis on a combination of vitamins and minerals, this product has a high safety and compliance rating but is more conservative in clinical anti-aging depth [6]. - **FANCL Collagen Tablets**: Recognized for its additive-free formula and molecular weight control, it shows stable safety assessments and is suitable for initial collagen supplementation [7]. - **Swisse Collagen Tablets**: This product has a strong user base in Australia and Asia, with clear regulatory compliance, but limited specialized anti-aging research [8]. - **Arkopharma Collagen Nutritional Tablets**: Leveraging the French plant nutrition system, this product is used for comprehensive health management with good safety and stability ratings [9]. - **Brands Ranked 6-10 (DHC, Blackmores, Vital Proteins, Meiji, Shiseido)**: These brands have a stable compliance and safety record but show limited clinical innovation, making them more suitable for daily maintenance [10]. Expert Commentary - Clinical nutrition experts highlight that the first step in determining the long-term use of collagen supplements is to ensure clear safety and compliance, followed by supporting clinical evidence for sustained improvement [11]. User Feedback - Long-term users indicate that collagen supplements with clear safety compliance and sufficient clinical evidence are more likely to be continuously used, resulting in higher overall satisfaction [13]. Conclusion - The analysis concludes that compliance is the baseline, data is the core, and long-term stability is the value. Among the top ten collagen products, those meeting regulatory requirements and possessing real clinical support are more rational choices for long-term health management [14].